null
SMILES CN(C)CCCSc1ccccc1NC(=O)\C=C\c1ccccc1
InChI Key InChIKey=RSUVYMGADVXGOU-BUHFOSPRSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 33 hits for monomerid = 50016900
Target5-hydroxytryptamine receptor 2A(Rattus norvegicus (rat))
Emory University
Curated by PDSP Ki Database
Emory University
Curated by PDSP Ki Database
Affinity DataKi: 4nMAssay Description:Binding affinity to rat cortical membranes at 5-hydroxytryptamine 2 receptor binding site by using [3H]- DOB as a radioligandMore data for this Ligand-Target Pair
Affinity DataKi: 4nMAssay Description:Binding affinity to rat cortical membranes at 5-hydroxytryptamine 2 (5-HT2) receptor using [3H]KET as a radioligandMore data for this Ligand-Target Pair
Affinity DataKi: 4nMAssay Description:Binding affinity to 5-hydroxytryptamine 2 receptor in rat frontal cortical membranes by [3H]- KET displacement.More data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 2A(Rattus norvegicus (rat))
Emory University
Curated by PDSP Ki Database
Emory University
Curated by PDSP Ki Database
Target5-hydroxytryptamine receptor 2A(Rattus norvegicus (rat))
Emory University
Curated by PDSP Ki Database
Emory University
Curated by PDSP Ki Database
Target5-hydroxytryptamine receptor 2A(Rattus norvegicus (rat))
Emory University
Curated by PDSP Ki Database
Emory University
Curated by PDSP Ki Database
Target5-hydroxytryptamine receptor 2A(Rattus norvegicus (rat))
Emory University
Curated by PDSP Ki Database
Emory University
Curated by PDSP Ki Database
Target5-hydroxytryptamine receptor 2A(Rattus norvegicus (rat))
Emory University
Curated by PDSP Ki Database
Emory University
Curated by PDSP Ki Database
Target5-hydroxytryptamine receptor 2A(Rattus norvegicus (rat))
Emory University
Curated by PDSP Ki Database
Emory University
Curated by PDSP Ki Database
Affinity DataKi: 13nMAssay Description:Displacement of [3H]ketanserin from human 5HT2A receptor expressed in human HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 17nMAssay Description:Displacement of [3H]ketanserin from human 5HT2A receptor expressed in human A549 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 22nMAssay Description:Displacement of [3H]INBMeO from human 5HT2A receptor expressed in human HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 24nMAssay Description:Displacement of [3H]INBMeO from human 5HT2A receptor expressed in human A549 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 200nMAssay Description:Evaluated for the binding affinity to porcine choroid plexus at 5-hydroxytryptamine 2C receptor binding site by using [3H]-MES as a radioligand.More data for this Ligand-Target Pair
Affinity DataKi: 1.00E+3nMAssay Description:Binding affinity (Ki) to rat cortical membranes at 5-HT1B binding site by using [125 I] ICYP as a radioligand.More data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
INSERM U. 114
Curated by PDSP Ki Database
INSERM U. 114
Curated by PDSP Ki Database
Affinity DataKi: 3.50E+3nMAssay Description:Evaluated for binding affinity towards rat cortical membranes at 5-hydroxytryptamine 1 receptor binding site by using [3H]-5-HT as a radioligand.More data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
INSERM U. 114
Curated by PDSP Ki Database
INSERM U. 114
Curated by PDSP Ki Database
TargetD(2) dopamine receptor(Rattus norvegicus (rat))
DuPont Merck Pharmaceutical Company
Curated by PDSP Ki Database
DuPont Merck Pharmaceutical Company
Curated by PDSP Ki Database
Affinity DataIC50: 2nMAssay Description:Concentration necessary to achieve half maximal inhibition of [3H]ketanserin binding to 5-hydroxytryptamine 2 receptor at 1 uMMore data for this Ligand-Target Pair
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
University of North Carolina
Curated by ChEMBL
University of North Carolina
Curated by ChEMBL
Affinity DataIC50: 182nMAssay Description:The compound was tested for affinity towards sigma-3 receptorMore data for this Ligand-Target Pair
Target InfoPDBMMDBNCI pathwayReactome pathwayKEGG
UniProtKB/SwissProtUniProtKB/TrEMBL
B.MOADDrugBankGoogleScholar
UniProtKB/SwissProtUniProtKB/TrEMBL
B.MOADDrugBankGoogleScholar
In DepthDetails
TargetPlatelet glycoprotein VI(Homo sapiens (Human))
Academy of Scientific and Innovative Research
Curated by ChEMBL
Academy of Scientific and Innovative Research
Curated by ChEMBL
Affinity DataIC50: 3.50E+4nMAssay Description:Antagonist activity at GP6 receptor in human platelet rich plasma assessed as inhibition of CRP-induced platelet aggregation preincubated for 60 sec ...More data for this Ligand-Target Pair
TargetPlatelet glycoprotein VI(Homo sapiens (Human))
Academy of Scientific and Innovative Research
Curated by ChEMBL
Academy of Scientific and Innovative Research
Curated by ChEMBL
Affinity DataIC50: 4.00E+4nMAssay Description:Antagonist activity at GP6 receptor in human platelet rich plasma assessed as inhibition of collagen-induced platelet aggregation preincubated for 60...More data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 2A(Rattus norvegicus (rat))
Emory University
Curated by PDSP Ki Database
Emory University
Curated by PDSP Ki Database
Affinity DataIC50: 14.8nMAssay Description:In vitro binding affinity for serotonin 5-hydroxytryptamine 2A receptor of rat cerebral cortex using [3H]ketanserin as radioligandMore data for this Ligand-Target Pair
TargetPlatelet glycoprotein VI(Homo sapiens (Human))
Academy of Scientific and Innovative Research
Curated by ChEMBL
Academy of Scientific and Innovative Research
Curated by ChEMBL
Affinity DataIC50: 4.00E+4nMAssay Description:Antagonist activity at GP6 in human platelet assessed as reduction in collagen-induced platelet-aggregation preincubated for 60 secs followed by coll...More data for this Ligand-Target Pair
TargetPlatelet glycoprotein VI(Homo sapiens (Human))
Academy of Scientific and Innovative Research
Curated by ChEMBL
Academy of Scientific and Innovative Research
Curated by ChEMBL
Affinity DataIC50: 3.50E+4nMAssay Description:Antagonist activity at GP6 in human platelet assessed as reduction in CRP-induced platelet-aggregation preincubated for 60 secs followed by collagen ...More data for this Ligand-Target Pair
Affinity DataIC50: 5.00E+3nMAssay Description:This is a review article. Please point to the original journal.More data for this Ligand-Target Pair