null

SMILES O=C(NC1CCN(CCc2c[nH]c3ccccc23)CC1)c1ccccc1

InChI Key InChIKey=JXZZEXZZKAWDSP-UHFFFAOYSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 24 hits for monomerid = 50033113   

TargetAlpha-1A adrenergic receptor(Homo sapiens (Human))
SmithKline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50033113(CHEMBL279516 | INDORAMIN | INDORAMINE | INDORAMINN...)copy SMILEScopy InChI
Affinity DataKi:  3.70nMAssay Description:The compound was tested for binding affinity against Alpha-1A adrenergic receptor from human clones.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q20G3J6WPubMed
Target5-hydroxytryptamine receptor 7(Rattus norvegicus (rat))
TBA

Curated by PDSP Ki Database
LigandPNGBDBM50033113(CHEMBL279516 | INDORAMIN | INDORAMINE | INDORAMINN...)copy SMILEScopy InChI
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KD1WC3PubMed
TargetAlpha-1A adrenergic receptor(Rattus norvegicus (Rat))
TBA

Curated by PDSP Ki Database
LigandPNGBDBM50033113(CHEMBL279516 | INDORAMIN | INDORAMINE | INDORAMINN...)copy SMILEScopy InChI
Affinity DataKi:  5.90nMMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2TT4PFZPubMed
TargetAlpha-1A adrenergic receptor(CALF)
SmithKline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50033113(CHEMBL279516 | INDORAMIN | INDORAMINE | INDORAMINN...)copy SMILEScopy InChI
Affinity DataKi:  12nMAssay Description:The compound was tested for binding affinity against Alpha-1A adrenergic receptor from bovine clones.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q20G3J6WPubMed
TargetAlpha-1A/Alpha-1B/Alpha-1D adrenergic receptor(Rattus norvegicus (rat))
TBA

Curated by ChEMBL
LigandPNGBDBM50033113(CHEMBL279516 | INDORAMIN | INDORAMINE | INDORAMINN...)copy SMILEScopy InChI
Affinity DataKi:  25nMAssay Description:Affinity for alpha-1 adrenoceptor of rat cerebral cortex was determined by ligand binding using [3H]prazosin.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2TH8PW6PubMed
TargetAlpha-1B adrenergic receptor(Homo sapiens (Human))
SmithKline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50033113(CHEMBL279516 | INDORAMIN | INDORAMINE | INDORAMINN...)copy SMILEScopy InChI
Affinity DataKi:  25nMAssay Description:The compound was tested for binding affinity against Alpha-1B adrenergic receptor, from hamster clones.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q20G3J6WPubMed
TargetAlpha-1B adrenergic receptor(Homo sapiens (Human))
SmithKline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50033113(CHEMBL279516 | INDORAMIN | INDORAMINE | INDORAMINN...)copy SMILEScopy InChI
Affinity DataKi:  29nMAssay Description:The compound was tested for binding affinity against Alpha-1B adrenergic receptor, from human clones.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q20G3J6WPubMed
TargetAlpha-1D adrenergic receptor(Homo sapiens (Human))
SmithKline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50033113(CHEMBL279516 | INDORAMIN | INDORAMINE | INDORAMINN...)copy SMILEScopy InChI
Affinity DataKi:  110nMAssay Description:Binding affinity against Alpha-1D adrenergic receptor, from human clones.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q20G3J6WPubMed
TargetAlpha-1B adrenergic receptor(Rattus norvegicus (rat))
Duke University

Curated by PDSP Ki Database
LigandPNGBDBM50033113(CHEMBL279516 | INDORAMIN | INDORAMINE | INDORAMINN...)copy SMILEScopy InChI
Affinity DataKi:  226nMMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2X928SGPubMed
TargetAlpha-2C adrenergic receptor(Homo sapiens (Human))
SmithKline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50033113(CHEMBL279516 | INDORAMIN | INDORAMINE | INDORAMINN...)copy SMILEScopy InChI
Affinity DataKi:  476nMAssay Description:Binding affinity against Alpha-2C adrenergic receptor from human clones.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q20G3J6WPubMed
TargetAlpha-2B adrenergic receptor(Homo sapiens (Human))
SmithKline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50033113(CHEMBL279516 | INDORAMIN | INDORAMINE | INDORAMINN...)copy SMILEScopy InChI
Affinity DataKi:  528nMAssay Description:Binding affinity against Alpha-2B adrenergic receptor from human clones.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q20G3J6WPubMed
TargetAlpha-2C adrenergic receptor(RAT)
University of California

Curated by PDSP Ki Database
LigandPNGBDBM50033113(CHEMBL279516 | INDORAMIN | INDORAMINE | INDORAMINN...)copy SMILEScopy InChI
Affinity DataKi:  590nMMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2F18X7BPubMed
TargetAlpha-1D adrenergic receptor(Rattus norvegicus (Rat))
SmithKline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50033113(CHEMBL279516 | INDORAMIN | INDORAMINE | INDORAMINN...)copy SMILEScopy InChI
Affinity DataKi:  611nMAssay Description:Binding affinity against Alpha-1D adrenergic receptor, from rat clones.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q20G3J6WPubMed
TargetAlpha-1A adrenergic receptor(Rattus norvegicus (Rat))
TBA

Curated by PDSP Ki Database
LigandPNGBDBM50033113(CHEMBL279516 | INDORAMIN | INDORAMINE | INDORAMINN...)copy SMILEScopy InChI
Affinity DataKi:  611nMMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2X928SGPubMed
TargetAlpha-2A adrenergic receptor(Homo sapiens (Human))
SmithKline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50033113(CHEMBL279516 | INDORAMIN | INDORAMINE | INDORAMINN...)copy SMILEScopy InChI
Affinity DataKi:  2.24E+3nMAssay Description:The compound was tested for binding affinity against Alpha-2A adrenergic receptor from human clones.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q20G3J6WPubMed
TargetAlpha-2C adrenergic receptor(RAT)
University of California

Curated by PDSP Ki Database
LigandPNGBDBM50033113(CHEMBL279516 | INDORAMIN | INDORAMINE | INDORAMINN...)copy SMILEScopy InChI
Affinity DataKi:  6.12E+3nMMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2F18X7BPubMed
TargetAlpha-1A adrenergic receptor(Rattus norvegicus (Rat))
TBA

Curated by PDSP Ki Database
LigandPNGBDBM50033113(CHEMBL279516 | INDORAMIN | INDORAMINE | INDORAMINN...)copy SMILEScopy InChI
Affinity DataKi:  6.50E+3nMMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2TT4PFZPubMed
LigandPNGBDBM50033113(CHEMBL279516 | INDORAMIN | INDORAMINE | INDORAMINN...)copy SMILEScopy InChI
Affinity DataKi:  1.20E+4nMAssay Description:Affinity for alpha-2 adrenergic receptor of rat cerebral cortex was determined by ligand binding using [3H]yohimbine.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2TH8PW6PubMed
TargetATP-binding cassette sub-family C member 4(Homo sapiens (Human))
Amgen Inc

Curated by ChEMBL
LigandPNGBDBM50033113(CHEMBL279516 | INDORAMIN | INDORAMINE | INDORAMINN...)copy SMILEScopy InChI
Affinity DataIC50: 1.33E+5nMAssay Description:Inhibition of human MRP4 overexpressed in Sf9 cell membrane vesicles assessed as uptake of [3H]-estradiol-17beta-D-glucuronide in presence of ATP and...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2JM2D2DPubMed
TargetBile salt export pump(Homo sapiens (Human))
Amgen Inc

Curated by ChEMBL
LigandPNGBDBM50033113(CHEMBL279516 | INDORAMIN | INDORAMINE | INDORAMINN...)copy SMILEScopy InChI
Affinity DataIC50: 1.33E+5nMAssay Description:Inhibition of human BSEP overexpressed in Sf9 cell membrane vesicles assessed as uptake of [3H]-taurocholate in presence of ATP measured after 15 to ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2JM2D2DPubMed
TargetATP-binding cassette sub-family C member 2(Homo sapiens (Human))
Amgen Inc

Curated by ChEMBL
LigandPNGBDBM50033113(CHEMBL279516 | INDORAMIN | INDORAMINE | INDORAMINN...)copy SMILEScopy InChI
Affinity DataIC50: 1.33E+5nMAssay Description:Inhibition of human MRP2 overexpressed in Sf9 cell membrane vesicles assessed as uptake of [3H]-estradiol-17beta-D-glucuronide in presence of ATP and...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2JM2D2DPubMed
TargetATP-binding cassette sub-family C member 3(Homo sapiens (Human))
Amgen Inc

Curated by ChEMBL
LigandPNGBDBM50033113(CHEMBL279516 | INDORAMIN | INDORAMINE | INDORAMINN...)copy SMILEScopy InChI
Affinity DataIC50: 1.33E+5nMAssay Description:Inhibition of human MRP3 overexpressed in Sf9 insect cell membrane vesicles assessed as uptake of [3H]-estradiol-17beta-D-glucuronide in presence of ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2JM2D2DPubMed
TargetBile salt export pump(Homo sapiens (Human))
Amgen Inc

Curated by ChEMBL
LigandPNGBDBM50033113(CHEMBL279516 | INDORAMIN | INDORAMINE | INDORAMINN...)copy SMILEScopy InChI
Affinity DataIC50: 1.35E+5nMAssay Description:Inhibition of human BSEP expressed in fall armyworm sf9 cell plasma membrane vesicles assessed as reduction in vesicle-associated [3H]-taurocholate t...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26Q20JNPubMed
TargetBile salt export pump(Homo sapiens (Human))
Amgen Inc

Curated by ChEMBL
LigandPNGBDBM50033113(CHEMBL279516 | INDORAMIN | INDORAMINE | INDORAMINN...)copy SMILEScopy InChI
Affinity DataIC50: 1.09E+5nMAssay Description:Inhibition of human BSEP expressed in baculovirus transfected fall armyworm Sf21 cell membranes vesicles assessed as reduction in ATP-dependent [3H]-...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZP488MPubMed