null

SMILES COc1cc(\C=C(/C#N)C(N)=O)cc(CSc2ccc3ccccc3c2)c1O

InChI Key InChIKey=PWAFUGMDLMAVBQ-CAOOACKPSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50036690   

TargetEpidermal growth factor receptor(Homo sapiens (Human))
Hebrew University of Jerusalem

Curated by ChEMBL
LigandPNGBDBM50036690(2-Cyano-3-[4-hydroxy-3-methoxy-5-(naphthalen-2-yls...)copy SMILEScopy InChI
Affinity DataIC50: 1.70E+3nMAssay Description:Inhibitiory concentration against EGF receptor by autophosphorylationMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2MP52B9PubMed
TargetEpidermal growth factor receptor/Receptor tyrosine-protein kinase erbB-2(Homo sapiens (Human))
Hebrew University of Jerusalem

Curated by ChEMBL
LigandPNGBDBM50036690(2-Cyano-3-[4-hydroxy-3-methoxy-5-(naphthalen-2-yls...)copy SMILEScopy InChI
Affinity DataIC50: 4.60E+3nMAssay Description:Inhibitory concentration against ErbB2/neu (HER-2) by autophosphorylationMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2MP52B9PubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Hebrew University of Jerusalem

Curated by ChEMBL
LigandPNGBDBM50036690(2-Cyano-3-[4-hydroxy-3-methoxy-5-(naphthalen-2-yls...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibitiory concentration against EGF receptor by polyGAT phosphorylationMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2MP52B9PubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Hebrew University of Jerusalem

Curated by ChEMBL
LigandPNGBDBM50036690(2-Cyano-3-[4-hydroxy-3-methoxy-5-(naphthalen-2-yls...)copy SMILEScopy InChI
Affinity DataIC50: 6.60E+3nMAssay Description:Inhibitiory concentration against EGF receptor by polyGAT phosphorylationMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2MP52B9PubMed