null

SMILES CN(C)Cc1ccc2CN(CCc2c1)C(=O)c1cc2cc(Cl)ccc2n1C

InChI Key InChIKey=IJLVCMAAMCBQNU-UHFFFAOYSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50045833   

TargetPotassium voltage-gated channel subfamily E member 1(Homo sapiens (Human))
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM50045833(CHEMBL3314349)copy SMILEScopy InChI
Affinity DataIC50: 1.05E+4nMAssay Description:Inhibition of human cardiac slowly activating delayed rectifier K+ channel expressed in CHO cells by electrophysiology assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MP54W9PubMed
TargetSodium channel protein type 5 subunit alpha(Homo sapiens (Human))
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM50045833(CHEMBL3314349)copy SMILEScopy InChI
Affinity DataIC50: 1.03E+4nMAssay Description:Inhibition of human Nav1.5 expressed in CHO cells by electrophysiology assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MP54W9PubMed
TargetPyroglutamylated RF-amide peptide receptor(Homo sapiens (Human))
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM50045833(CHEMBL3314349)copy SMILEScopy InChI
Affinity DataIC50: 70nMAssay Description:Inhibition of human GPR103 receptor expressed in CHOK1 cells by IP-1 assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MP54W9PubMed
TargetCytochrome P450 2D6(Homo sapiens (Human))
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM50045833(CHEMBL3314349)copy SMILEScopy InChI
Affinity DataIC50: 2.90E+3nMAssay Description:Inhibition of human CYP2D6 after 20 to 50 mins by high-throughput fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MP54W9PubMed
TargetPyroglutamylated RF-amide peptide receptor(Homo sapiens (Human))
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM50045833(CHEMBL3314349)copy SMILEScopy InChI
Affinity DataIC50: 70nMAssay Description:Displacement of [125I]QRFP43 from human GPR103 receptor expressed in HEK cells after 90 mins incubation by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MP54W9PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM50045833(CHEMBL3314349)copy SMILEScopy InChI
Affinity DataIC50: 4.90E+3nMAssay Description:Inhibition of human ERG expressed in CHO cells by electrophysiology assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MP54W9PubMed