null
SMILES CCCCC(=O)N(Cc1ccc(cc1)-c1ccccc1-c1nnn[nH]1)[C@@H](C(C)C)C(O)=O
InChI Key InChIKey=ACWBQPMHZXGDFX-QFIPXVFZSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 14 hits for monomerid = 50049186
TargetType-1 angiotensin II receptor(Homo sapiens (Human))
Bahcesehir University (BAU)
Curated by ChEMBL
Bahcesehir University (BAU)
Curated by ChEMBL
Affinity DataKi: 3nMAssay Description:Displacement of [125I-Sar1-Ile8]-Ang2 from human angiotensin 2 receptor type 1 receptor expressed in HEK293 cells after 1 hr by gamma counting analys...More data for this Ligand-Target Pair
TargetType-1 angiotensin II receptor(Homo sapiens (Human))
Bahcesehir University (BAU)
Curated by ChEMBL
Bahcesehir University (BAU)
Curated by ChEMBL
Affinity DataKi: 4.70E+3nMAssay Description:Inhibition constant against Angiotensin II receptor, type 1 was determinedMore data for this Ligand-Target Pair
TargetType-2 angiotensin II receptor(Homo sapiens (Human))
Theravance Biopharma US Inc.
Curated by ChEMBL
Theravance Biopharma US Inc.
Curated by ChEMBL
Affinity DataKi: <1.00E+4nMAssay Description:Displacement of Europium-labeled angiotensin-2 from human AT2 receptor expressed in CHOK1 cell membranes after 120 mins by DELFIAMore data for this Ligand-Target Pair
Affinity DataIC50: 3.11E+4nMAssay Description:Inhibition of human BSEP expressed in baculovirus transfected fall armyworm Sf21 cell membranes vesicles assessed as reduction in ATP-dependent [3H]-...More data for this Ligand-Target Pair
Affinity DataIC50: 1.33E+5nMAssay Description:Inhibition of human MRP2 overexpressed in Sf9 cell membrane vesicles assessed as uptake of [3H]-estradiol-17beta-D-glucuronide in presence of ATP and...More data for this Ligand-Target Pair
TargetType-1 angiotensin II receptor(Homo sapiens (Human))
Bahcesehir University (BAU)
Curated by ChEMBL
Bahcesehir University (BAU)
Curated by ChEMBL
Affinity DataIC50: 7.40nMAssay Description:Displacement of [125-I]-[Sar1, AngII from AT1R (unknown origin) expressed in Escherichia coli BL 21 (DE3) incubated for 2 hrs by radioimmunoassayMore data for this Ligand-Target Pair
Affinity DataIC50: 1.33E+5nMAssay Description:Inhibition of human MRP4 overexpressed in Sf9 cell membrane vesicles assessed as uptake of [3H]-estradiol-17beta-D-glucuronide in presence of ATP and...More data for this Ligand-Target Pair
Affinity DataIC50: 1.33E+5nMAssay Description:Inhibition of human MRP3 overexpressed in Sf9 insect cell membrane vesicles assessed as uptake of [3H]-estradiol-17beta-D-glucuronide in presence of ...More data for this Ligand-Target Pair
Affinity DataKd: 1.00E+5nMAssay Description:Binding affinity to recombinant GP6 (unknown origin) at protein to compound ratio of 1 : 1 to 1 : 10 by 2D 15N-1H TROSY-HSQC NMR spectroscopyMore data for this Ligand-Target Pair
Affinity DataEC50: 1.60E+4nMAssay Description:Agonist activity at human BLT2 overexpressed in CHO-K1 cells assessed as accumulation of inositol monophosphate measured after 90 mins by HTRF assayMore data for this Ligand-Target Pair
Affinity DataIC50: 3.40nMAssay Description:Displacement of [125I]Sar1,Ile8-Ang2 from AT1 receptor in Wistar rat hepatic membraneMore data for this Ligand-Target Pair
TargetType-1 angiotensin II receptor(Homo sapiens (Human))
Bahcesehir University (BAU)
Curated by ChEMBL
Bahcesehir University (BAU)
Curated by ChEMBL
Affinity DataIC50: 2.70nMAssay Description:Tested for inhibition of Angiotensin II receptor, type 1 in the absence of bovine serum albumin (BSA)More data for this Ligand-Target Pair
Affinity DataIC50: 1.90nMAssay Description:Binding affinity for rat angiotensin II receptor, type 1More data for this Ligand-Target Pair
Affinity DataIC50: 1.33E+5nMAssay Description:Inhibition of human BSEP overexpressed in Sf9 cell membrane vesicles assessed as uptake of [3H]-taurocholate in presence of ATP measured after 15 to ...More data for this Ligand-Target Pair