null

SMILES NCCc1c[nH]c2ccc(OCc3ccc(COc4ccc5[nH]cc(CCN)c5c4)cc3)cc12

InChI Key InChIKey=IFTLFEAARDEHJJ-UHFFFAOYSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50054974   

Target5-hydroxytryptamine receptor 1B(Homo sapiens (Human))
Theravance, Inc.

Curated by ChEMBL
LigandPNGBDBM50054974(2-(5-((4-((3-(2-aminoethyl)-1H-indol-5-yloxy)methy...)copy SMILEScopy InChI
Affinity DataKi:  0.100nMAssay Description:Displacement of [3H]5-hydroxytryptamine from human cloned 5HT1B receptor expressed in CHOK1 cells by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26T0MDKPubMed
Target5-hydroxytryptamine receptor 1B(Homo sapiens (Human))
Theravance, Inc.

Curated by ChEMBL
LigandPNGBDBM50054974(2-(5-((4-((3-(2-aminoethyl)-1H-indol-5-yloxy)methy...)copy SMILEScopy InChI
Affinity DataKi:  0.100nMAssay Description:Ability to inhibit the forskolin-stimulated c-AMP formation mediated by human 5-hydroxytryptamine 1B receptor in CHO-K1 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23B5Z7MPubMed
Target5-hydroxytryptamine receptor 1D(Homo sapiens (Human))
Centre de Recherche Pierre Fabre

Curated by ChEMBL
LigandPNGBDBM50054974(2-(5-((4-((3-(2-aminoethyl)-1H-indol-5-yloxy)methy...)copy SMILEScopy InChI
Affinity DataKi:  0.110nMAssay Description:Ability to inhibit the forskolin-stimulated c-AMP formation mediated by human 5-hydroxytryptamine 1D receptor in CHO-K1 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23B5Z7MPubMed
Target5-hydroxytryptamine receptor 1D(Homo sapiens (Human))
Centre de Recherche Pierre Fabre

Curated by ChEMBL
LigandPNGBDBM50054974(2-(5-((4-((3-(2-aminoethyl)-1H-indol-5-yloxy)methy...)copy SMILEScopy InChI
Affinity DataKi:  0.110nMAssay Description:Displacement of [3H]5-hydroxytryptamine from human cloned 5HT1D receptor expressed in CHOK1 cells by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26T0MDKPubMed
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Theravance, Inc.

Curated by ChEMBL
LigandPNGBDBM50054974(2-(5-((4-((3-(2-aminoethyl)-1H-indol-5-yloxy)methy...)copy SMILEScopy InChI
Affinity DataKi:  1.60nMAssay Description:Binding affinity to 5HT1A receptorMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26T0MDKPubMed
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Theravance, Inc.

Curated by ChEMBL
LigandPNGBDBM50054974(2-(5-((4-((3-(2-aminoethyl)-1H-indol-5-yloxy)methy...)copy SMILEScopy InChI
Affinity DataKi:  1.60nMAssay Description:Ability to inhibit the forskolin-stimulated c-AMP formation mediated by human 5-hydroxytryptamine 1A receptor in CHO-K1 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23B5Z7MPubMed
Target5-hydroxytryptamine receptor 1B(Homo sapiens (Human))
Theravance, Inc.

Curated by ChEMBL
LigandPNGBDBM50054974(2-(5-((4-((3-(2-aminoethyl)-1H-indol-5-yloxy)methy...)copy SMILEScopy InChI
Affinity DataEC50:  3nMAssay Description:Inhibition of forskolin-stimulated c-AMP formation by human 5-hydroxytryptamine 1B receptor expressed in CHO-K1 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23B5Z7MPubMed