null

SMILES Oc1ccc(\C=C\C(=O)\C=C\c2ccc(O)cc2)cc1

InChI Key InChIKey=FTEGUKWEUQPKIS-YDWXAUTNSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 11 hits for monomerid = 50067044   

Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Wenzhou Medical College

Curated by ChEMBL
LigandPNGBDBM50067044((1E,4E)-1,5-Bis-(4-hydroxy-phenyl)-penta-1,4-dien-...)copy SMILEScopy InChI
Affinity DataIC50: 4.42E+3nMAssay Description:Inhibition of 11beta-HSD1 in human liver microsomes using [3H]-cortisone as substrate assessed as formation of cortisol after 60 to 90 mins by radiom...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27D2WJMPubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Rattus norvegicus (rat))
Wenzhou Medical College

Curated by ChEMBL
LigandPNGBDBM50067044((1E,4E)-1,5-Bis-(4-hydroxy-phenyl)-penta-1,4-dien-...)copy SMILEScopy InChI
Affinity DataIC50: 986nMAssay Description:Inhibition of 11beta-HSD1 in Sprague-Dawley rat leydig cells at 100 uMMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27D2WJMPubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Wenzhou Medical College

Curated by ChEMBL
LigandPNGBDBM50067044((1E,4E)-1,5-Bis-(4-hydroxy-phenyl)-penta-1,4-dien-...)copy SMILEScopy InChI
Affinity DataIC50: 832nMAssay Description:Inhibition of human 11beta-HSD1 transfected in CHOP cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27D2WJMPubMed
TargetCytochrome P450 2C9(Homo sapiens (Human))
Vrije Universiteit

Curated by ChEMBL
LigandPNGBDBM50067044((1E,4E)-1,5-Bis-(4-hydroxy-phenyl)-penta-1,4-dien-...)copy SMILEScopy InChI
Affinity DataIC50: 1.80E+3nMAssay Description:Inhibition of human recombinant CYP2C9More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26D5SRWPubMed
TargetCytochrome P450 2D6(Homo sapiens (Human))
Vrije Universiteit

Curated by ChEMBL
LigandPNGBDBM50067044((1E,4E)-1,5-Bis-(4-hydroxy-phenyl)-penta-1,4-dien-...)copy SMILEScopy InChI
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibition of human recombinant CYP2D6More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26D5SRWPubMed
TargetTissue factor(Homo sapiens (Human))TBA
LigandPNGBDBM50067044((1E,4E)-1,5-Bis-(4-hydroxy-phenyl)-penta-1,4-dien-...)copy SMILEScopy InChI
Affinity DataIC50: 2.60nMAssay Description:Inhibition of tissue factor in Homo sapiens (human) THP1-cells using factor 10a chromogenic substrate assessed as inhibition of LPS-iduced procoagula...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23F4SJ7
TargetCytochrome P450 2D6(Homo sapiens (Human))
Vrije Universiteit

Curated by ChEMBL
LigandPNGBDBM50067044((1E,4E)-1,5-Bis-(4-hydroxy-phenyl)-penta-1,4-dien-...)copy SMILEScopy InChI
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibition of human recombinant CYP2D6More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26D5SRWPubMed
TargetTyrosinase(Homo sapiens (Human))
Universiti Putra Malaysia

Curated by ChEMBL
LigandPNGBDBM50067044((1E,4E)-1,5-Bis-(4-hydroxy-phenyl)-penta-1,4-dien-...)copy SMILEScopy InChI
Affinity DataIC50: 7.91E+4nMAssay Description:Inhibition of tyrosinaseMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29S1R35PubMed
TargetIntegrase(Human immunodeficiency virus 1)
Universit£ di Roma"La Sapienza"

Curated by ChEMBL
LigandPNGBDBM50067044((1E,4E)-1,5-Bis-(4-hydroxy-phenyl)-penta-1,4-dien-...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+5nMAssay Description:Compound concentration required to reduce HIV-1 Integrase 3'-processing activity by 50%More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29024G3PubMed
TargetIntegrase(Human immunodeficiency virus 1)
Universit£ di Roma"La Sapienza"

Curated by ChEMBL
LigandPNGBDBM50067044((1E,4E)-1,5-Bis-(4-hydroxy-phenyl)-penta-1,4-dien-...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibitory activity against HIV-1 Integrase (HIV-1-IN)More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q28W3FGVPubMed
TargetCytochrome P450 2C9(Homo sapiens (Human))
Vrije Universiteit

Curated by ChEMBL
LigandPNGBDBM50067044((1E,4E)-1,5-Bis-(4-hydroxy-phenyl)-penta-1,4-dien-...)copy SMILEScopy InChI
Affinity DataIC50: 1.80E+3nMAssay Description:Inhibition of human recombinant CYP2C9More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26D5SRWPubMed