null

SMILES COc1cc2cc(CO)c(CO)c(-c3ccnc(c3)-n3ccccc3=O)c2cc1OC

InChI Key InChIKey=SJQXOZSDYOZKJF-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50074890   

TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D(Homo sapiens (Human))
Tanabe Seiyaku Company, Ltd.

Curated by ChEMBL

LigandBDBM50074890(4'-(2,3-Bis-hydroxymethyl-6,7-dimethoxy-naphthalen...)copy SMILEScopy InChI

Affinity DataIC50: 80nMAssay Description:In vitro inhibition of Phosphodiesterase 4 from guinea pig lungMore data for this Ligand-Target Pair

Target InfoPDB
UniProtKB/SwissProt
antibodypediaantibodypediaantibodypediaantibodypediaGoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25M66DHPubMed

TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Tanabe Seiyaku Company, Ltd.

Curated by ChEMBL

LigandBDBM50074890(4'-(2,3-Bis-hydroxymethyl-6,7-dimethoxy-naphthalen...)copy SMILEScopy InChI

Affinity DataIC50: 4.00E+4nMAssay Description:Inhibition of Phosphodiesterase 5 of guinea pig lungMore data for this Ligand-Target Pair

Target InfoPDBMMDBReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaGoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25M66DHPubMed

TargetcGMP-inhibited 3',5'-cyclic phosphodiesterase 3A/3B(Homo sapiens (Human))
Tanabe Seiyaku Company, Ltd.

Curated by ChEMBL

LigandBDBM50074890(4'-(2,3-Bis-hydroxymethyl-6,7-dimethoxy-naphthalen...)copy SMILEScopy InChI

Affinity DataIC50: 2.00E+3nMAssay Description:In vitro inhibition of Phosphodiesterase 3 activity from guinea pig cardiac ventricleMore data for this Ligand-Target Pair

Target InfoPDBMMDB
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaantibodypediaGoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25M66DHPubMed

TargetDual specificity calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1A/1B/1C(Homo sapiens (Human))
Tanabe Seiyaku Company, Ltd.

Curated by ChEMBL

LigandBDBM50074890(4'-(2,3-Bis-hydroxymethyl-6,7-dimethoxy-naphthalen...)copy SMILEScopy InChI

Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of Phosphodiesterase 1 of guinea pig cardiac ventricleMore data for this Ligand-Target Pair

Target InfoPDBMMDBKEGG
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaantibodypediaantibodypediaGoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25M66DHPubMed