null
SMILES CCOc1ccccc1N\N=C1\C(C)=NN(C1=O)c1cc(O)cc(c1)-c1ccc(cc1)N(C)C
InChI Key InChIKey=BPJKUWXILSKTLE-FVDSYPCUSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 4 hits for monomerid = 50078022
TargetApoptosis regulator BAX(Homo sapiens (Human))
Universit£ di Napoli"Federico II"
Curated by ChEMBL
Universit£ di Napoli"Federico II"
Curated by ChEMBL
Affinity DataKi: 800nMAssay Description:Displacement of FITC-BIM from recombinant N-terminal GST-tagged human BAX expressed in Escherichia coli after 30 mins by fluorescence polarization as...More data for this Ligand-Target Pair
TargetApoptosis regulator Bcl-2(Homo sapiens (Human))
Universit£ di Napoli"Federico II"
Curated by ChEMBL
Universit£ di Napoli"Federico II"
Curated by ChEMBL
Affinity DataKi: 1.20E+4nMAssay Description:Displacement of FITC-BIM from recombinant human Bcl-2 expressed in Escherichia coli after 30 mins by fluorescence polarization assayMore data for this Ligand-Target Pair
Affinity DataKi: >1.00E+5nMAssay Description:Displacement of FITC-BIM from recombinant human Bcl-XL expressed in Escherichia coli after 30 mins by fluorescence polarization assayMore data for this Ligand-Target Pair
TargetApoptosis regulator BAX(Homo sapiens (Human))
Universit£ di Napoli"Federico II"
Curated by ChEMBL
Universit£ di Napoli"Federico II"
Curated by ChEMBL
Affinity DataEC50: 700nMAssay Description:Activation of Bax in human HuH7 cells assessed as inhibition of mitochondrial accumulation of fluorescent probe Mitotracker Red after 12 to 72 hrs by...More data for this Ligand-Target Pair