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SMILES Nc1nc2nn(CCCc3ccccc3)cc2c2nc(nn12)-c1ccco1

InChI Key InChIKey=KWNNEOHJLFPMKY-UHFFFAOYSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 15 hits for monomerid = 50082423   

TargetAdenosine receptor A2a(Homo sapiens (Human))
Universit£ di Padova

Curated by ChEMBL
LigandPNGBDBM50082423(2-(furan-2-yl)-8-(3-phenylpropyl)-8H-pyrazolo[4,3-...)copy SMILEScopy InChI
Affinity DataKi:  0.160nMAssay Description:Displacement of [3H]NECA from human adenosine A2A receptor expressed in CHO cellsChecked by AuthorMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23N23FXPubMed
TargetAdenosine receptor A2a(Homo sapiens (Human))
Universit£ di Padova

Curated by ChEMBL
LigandPNGBDBM50082423(2-(furan-2-yl)-8-(3-phenylpropyl)-8H-pyrazolo[4,3-...)copy SMILEScopy InChI
Affinity DataKi:  0.160nMAssay Description:Displacement of [3H]-SCH- 58261 from human adenosine A2A receptor expressed in CHO cells; range 0.06-0.48More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2D21WWTPubMed
TargetAdenosine receptor A2a(Homo sapiens (Human))
Universit£ di Padova

Curated by ChEMBL
LigandPNGBDBM50082423(2-(furan-2-yl)-8-(3-phenylpropyl)-8H-pyrazolo[4,3-...)copy SMILEScopy InChI
Affinity DataKi:  0.180nMAssay Description:Displacement of specific [3H]-SCH- 58261 binding at human Adenosine A2A receptor expressed in HEK-293 cellsMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q26972RXPubMed
TargetAdenosine receptor A2a(Rattus norvegicus (rat))
Università degli Studi di Ferrara

Curated by ChEMBL
LigandPNGBDBM50082423(2-(furan-2-yl)-8-(3-phenylpropyl)-8H-pyrazolo[4,3-...)copy SMILEScopy InChI
Affinity DataKi:  0.590nMAssay Description:Displacement of [3H]-SCH- 58261 from Adenosine A2A receptor in rat striatal membranesMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q26972RXPubMed
TargetAdenosine receptor A1(Homo sapiens (Human))
Università degli Studi di Ferrara

Curated by ChEMBL
LigandPNGBDBM50082423(2-(furan-2-yl)-8-(3-phenylpropyl)-8H-pyrazolo[4,3-...)copy SMILEScopy InChI
Affinity DataKi:  3nMAssay Description:Displacement of [3H]-DPCPX from human adenosine A1 receptor expressed in CHO cells; range 2.65-3.39More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2D21WWTPubMed
TargetAdenosine receptor A1(Homo sapiens (Human))
Università degli Studi di Ferrara

Curated by ChEMBL
LigandPNGBDBM50082423(2-(furan-2-yl)-8-(3-phenylpropyl)-8H-pyrazolo[4,3-...)copy SMILEScopy InChI
Affinity DataKi:  3nMAssay Description:Displacement of [3H]-DPCPX from human Adenosine A1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q26972RXPubMed
TargetAdenosine receptor A1(Rattus norvegicus (rat))
Università degli Studi di Ferrara

Curated by ChEMBL
LigandPNGBDBM50082423(2-(furan-2-yl)-8-(3-phenylpropyl)-8H-pyrazolo[4,3-...)copy SMILEScopy InChI
Affinity DataKi:  11nMAssay Description:Displacement of [3H]-DPCPX from Adenosine A1 receptor of rat brain membranesMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q26972RXPubMed
TargetAdenosine receptor A2b(Homo sapiens (Human))
Università degli Studi di Ferrara

Curated by ChEMBL
LigandPNGBDBM50082423(2-(furan-2-yl)-8-(3-phenylpropyl)-8H-pyrazolo[4,3-...)copy SMILEScopy InChI
Affinity DataKi:  49nMAssay Description:Displacement of [3H]-DPCPX from Adenosine A2b receptor expressed in CHO cells; range 38-63More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2D21WWTPubMed
TargetAdenosine receptor A3(Homo sapiens (Human))
Università degli Studi di Ferrara

Curated by ChEMBL
LigandPNGBDBM50082423(2-(furan-2-yl)-8-(3-phenylpropyl)-8H-pyrazolo[4,3-...)copy SMILEScopy InChI
Affinity DataKi:  430nMAssay Description:Displacement of [3H]-MRE3008-F20 from human adenosine A3 receptor expressed in CHO cells; range 378-488More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2D21WWTPubMed
TargetAdenosine receptor A3(Homo sapiens (Human))
Università degli Studi di Ferrara

Curated by ChEMBL
LigandPNGBDBM50082423(2-(furan-2-yl)-8-(3-phenylpropyl)-8H-pyrazolo[4,3-...)copy SMILEScopy InChI
Affinity DataKi:  430nMAssay Description:Binding affinity for human adenosine A3 receptorMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2183609PubMed
TargetAdenosine receptor A3(Homo sapiens (Human))
Università degli Studi di Ferrara

Curated by ChEMBL
LigandPNGBDBM50082423(2-(furan-2-yl)-8-(3-phenylpropyl)-8H-pyrazolo[4,3-...)copy SMILEScopy InChI
Affinity DataKi:  430nMAssay Description:Antagonist activity at human adenosine A3 receptorMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2VH5P5ZPubMed
TargetAdenosine receptor A3(Homo sapiens (Human))
Università degli Studi di Ferrara

Curated by ChEMBL
LigandPNGBDBM50082423(2-(furan-2-yl)-8-(3-phenylpropyl)-8H-pyrazolo[4,3-...)copy SMILEScopy InChI
Affinity DataKi:  430nMAssay Description:Binding affinity to human adenosine A3 receptorMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q22Z18GV
TargetAdenosine receptor A3(Homo sapiens (Human))
Università degli Studi di Ferrara

Curated by ChEMBL
LigandPNGBDBM50082423(2-(furan-2-yl)-8-(3-phenylpropyl)-8H-pyrazolo[4,3-...)copy SMILEScopy InChI
Affinity DataKi:  2.67E+3nMAssay Description:Displacement of [125]AB-MECA from human Adenosine A3 receptor expressed in HEK-293 cellsMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q26972RXPubMed
TargetAdenosine receptor A3(Homo sapiens (Human))
Università degli Studi di Ferrara

Curated by ChEMBL
LigandPNGBDBM50082423(2-(furan-2-yl)-8-(3-phenylpropyl)-8H-pyrazolo[4,3-...)copy SMILEScopy InChI
Affinity DataKi:  2.67E+3nMAssay Description:Displacement of [3H]NECA from human adenosine A3 receptor expressed in CHO cellsChecked by AuthorMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23N23FXPubMed
TargetAdenosine receptor A3(Homo sapiens (Human))
Università degli Studi di Ferrara

Curated by ChEMBL
LigandPNGBDBM50082423(2-(furan-2-yl)-8-(3-phenylpropyl)-8H-pyrazolo[4,3-...)copy SMILEScopy InChI
Affinity DataKi:  4.27E+5nMAssay Description:Displacement of [3H]MRE3008-F20 from human adenosine A3 receptor expressed in CHO cells after 120 minsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XP766QPubMed