null
SMILES CN1CCN(CC1)c1ccc(Nc2ncc(Cl)c(NC[C@H]3CCCO3)n2)cc1
InChI Key InChIKey=MMJSYUQCKWEFRW-QGZVFWFLSA-N
PDB links: 1 PDB ID matches this monomer.
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 10 hits for monomerid = 50084464
TargetTyrosine-protein kinase JAK2(Homo sapiens (Human))
University of South Florida
Curated by ChEMBL
University of South Florida
Curated by ChEMBL
Affinity DataIC50: 6nMAssay Description:Inhibition of human JAK2 using poly[Glu:Tyr] (4:1) peptide substrate by 33P Hotspot assayMore data for this Ligand-Target Pair
TargetNon-receptor tyrosine-protein kinase TYK2(Homo sapiens (Human))
University of South Florida
Curated by ChEMBL
University of South Florida
Curated by ChEMBL
Affinity DataIC50: 5nMAssay Description:Inhibition of human TYK2 using KKSRGDYMTMQIG peptide substrate by 33P Hotspot assayMore data for this Ligand-Target Pair
TargetFibroblast growth factor receptor 1(Homo sapiens (Human))
University of South Florida
Curated by ChEMBL
University of South Florida
Curated by ChEMBL
Affinity DataIC50: 160nMAssay Description:Inhibition of human FGFR1 using KKKSPGEYVNIEFG peptide substrate by 33P Hotspot assayMore data for this Ligand-Target Pair
TargetTyrosine-protein kinase ABL1(Homo sapiens (Human))
University of South Florida
Curated by ChEMBL
University of South Florida
Curated by ChEMBL
Affinity DataIC50: 206nMAssay Description:Inhibition of human ABL1 using EAIYAAPFAKKK peptide substrate by 33P Hotspot assayMore data for this Ligand-Target Pair
Affinity DataIC50: 56nMAssay Description:Inhibition of ACK1 kinase (unknown origin)More data for this Ligand-Target Pair
3D Structure (crystal)TargetALK tyrosine kinase receptor(Homo sapiens (Human))
University of South Florida
Curated by ChEMBL
University of South Florida
Curated by ChEMBL
Affinity DataIC50: 143nMAssay Description:Inhibition of human ALK using poly[Glu:Tyr] (4:1) peptide substrate by 33P Hotspot assayMore data for this Ligand-Target Pair
Affinity DataIC50: 136nMAssay Description:Inhibition of human LCK using peptide poly[Glu:Tyr] (4:1) substrate by 33P Hotspot assayMore data for this Ligand-Target Pair
TargetProto-oncogene tyrosine-protein kinase ROS(Homo sapiens (Human))
University of South Florida
Curated by ChEMBL
University of South Florida
Curated by ChEMBL
Affinity DataIC50: 124nMAssay Description:Inhibition of human ROS/ROS1 using KKKSPGEYVNIEFG peptide substrate by 33P Hotspot assayMore data for this Ligand-Target Pair
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
University of South Florida
Curated by ChEMBL
University of South Florida
Curated by ChEMBL
Affinity DataIC50: 438nMAssay Description:Inhibition of human c-Src using poly[Glu:Tyr] (4:1) peptide substrate by 33P Hotspot assayMore data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase Chk1(Homo sapiens (Human))
University of South Florida
Curated by ChEMBL
University of South Florida
Curated by ChEMBL
Affinity DataIC50: 154nMAssay Description:Inhibition of human CHK1 using KKKVSRSGLYRSPSMPENLNRPR peptide substrate by 33P Hotspot assayMore data for this Ligand-Target Pair