null
SMILES C[C@H]1CNCCCN1S(=O)(=O)c1cccc2cncc(F)c12
InChI Key InChIKey=QSKQVZWVLOIIEV-NSHDSACASA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 15 hits for monomerid = 50087135
In DepthDetails
TargetRho-associated protein kinase 1(Homo sapiens (Human))
Georgia Institute of Technology
Curated by ChEMBL
Georgia Institute of Technology
Curated by ChEMBL
Affinity DataIC50: 51nMAssay Description:Inhibition of ROCK1 (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 19nMAssay Description:Inhibition of ROCK2 (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 19nMAssay Description:Inhibition of ROCK2 (unknown origin)More data for this Ligand-Target Pair
TargetRho-associated protein kinase 1(Homo sapiens (Human))
Georgia Institute of Technology
Curated by ChEMBL
Georgia Institute of Technology
Curated by ChEMBL
Affinity DataIC50: 51nMAssay Description:Inhibition of ROCK1 (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 19nMAssay Description:Inhibition of N-terminal GST-fused human ROCK2 catalytic domain ( 1 to 553 residues) expressed in baculovirus expression system using Long S6 Kinase ...More data for this Ligand-Target Pair
TargetRho-associated protein kinase 1(Homo sapiens (Human))
Georgia Institute of Technology
Curated by ChEMBL
Georgia Institute of Technology
Curated by ChEMBL
Affinity DataIC50: 51nMAssay Description:Inhibition of N-terminal GST-fused human ROCK1 catalytic domain ( 1 to 477 residues) expressed in baculovirus expression system using Long S6 Kinase ...More data for this Ligand-Target Pair
TargetRho-associated protein kinase 1(Homo sapiens (Human))
Georgia Institute of Technology
Curated by ChEMBL
Georgia Institute of Technology
Curated by ChEMBL
TargetRho-associated protein kinase 1(Homo sapiens (Human))
Georgia Institute of Technology
Curated by ChEMBL
Georgia Institute of Technology
Curated by ChEMBL
TargetRho-associated protein kinase 1(Homo sapiens (Human))
Georgia Institute of Technology
Curated by ChEMBL
Georgia Institute of Technology
Curated by ChEMBL
Target InfoPDBMMDBNCI pathwayReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaGoogleScholar
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaGoogleScholar
In DepthDetails
Affinity DataIC50: 3.80nMAssay Description:Inhibition of human N-terminal GST-tagged ROCK2 expressed in baculovirus-infected insect cells using long S6 kinase peptide as substrate by radiometr...More data for this Ligand-Target Pair
Affinity DataIC50: 197nMAssay Description:Inhibition of human N-terminal GST-tagged ROCK2 expressed in baculovirus-infected insect cells using long S6 kinase peptide as substrate by radiometr...More data for this Ligand-Target Pair