null

SMILES O=S(=O)(NCC1CN(C1)C#N)c1ccccc1

InChI Key InChIKey=UIOWYXXRERXCMP-UHFFFAOYSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50095493   

TargetCathepsin K(Homo sapiens (Human))
Merck Frosst Centre for Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50095493(CHEMBL276169 | N-(1-Cyano-azetidin-3-ylmethyl)-ben...)copy SMILEScopy InChI
Affinity DataKi:  20nMAssay Description:Inhibitory constant of the compound against human cathepsin KMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2DV1J4RPubMed
TargetCathepsin K(Homo sapiens (Human))
Merck Frosst Centre for Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50095493(CHEMBL276169 | N-(1-Cyano-azetidin-3-ylmethyl)-ben...)copy SMILEScopy InChI
Affinity DataIC50: 50nMAssay Description:Inhibition of recombinant human Cathepsin K using Z-Phe-Arg-pNA as substrate preincubated with enzyme for 90 mins followed by substrate addition by f...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2K35Z63PubMed
TargetCathepsin K(Homo sapiens (Human))
Merck Frosst Centre for Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50095493(CHEMBL276169 | N-(1-Cyano-azetidin-3-ylmethyl)-ben...)copy SMILEScopy InChI
Affinity DataIC50: 17nMAssay Description:Inhibitory constant of the compound against human cathepsin KMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2DV1J4RPubMed
TargetCathepsin B(Homo sapiens (Human))
Merck Frosst Centre for Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50095493(CHEMBL276169 | N-(1-Cyano-azetidin-3-ylmethyl)-ben...)copy SMILEScopy InChI
Affinity DataIC50: 300nMAssay Description:Inhibitory activity tested against Human Cathepsin B using Z-Phe-Arg-pNA as substrateMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2DV1J4RPubMed
TargetCathepsin K(Homo sapiens (Human))
Merck Frosst Centre for Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50095493(CHEMBL276169 | N-(1-Cyano-azetidin-3-ylmethyl)-ben...)copy SMILEScopy InChI
Affinity DataIC50: 20nMAssay Description:Inhibitory activity tested against Human Cathepsin K using Z-Phe-Arg-pNA as substrateMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2DV1J4RPubMed
TargetProcathepsin L(Homo sapiens (Human))
Merck Frosst Centre for Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50095493(CHEMBL276169 | N-(1-Cyano-azetidin-3-ylmethyl)-ben...)copy SMILEScopy InChI
Affinity DataIC50: 50nMAssay Description:Inhibitory activity tested against Human Cathepsin L using Z-Phe-Arg-pNA as substrateMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2DV1J4RPubMed