null

SMILES COc1cccc(c1)-c1cn(C2CC(C2)C(=O)NCCO)c2ncnc(N)c12

InChI Key InChIKey=VNYKLXOIIZFVQW-UHFFFAOYSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50097944   

TargetProto-oncogene tyrosine-protein kinase Src(Gallus gallus (Chicken))
Novartis Pharma Research

Curated by ChEMBL
LigandPNGBDBM50097944(3-[4-Amino-5-(3-methoxy-phenyl)-pyrrolo[2,3-d]pyri...)copy SMILEScopy InChI
Affinity DataIC50: 4.00E+3nMAssay Description:Inhibition of p60 c-Src tyrosine kinase mediated phosphorylation of Fak in IC8.1 fibroblastsMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2FF3RMFPubMed
TargetProto-oncogene tyrosine-protein kinase Src(Gallus gallus (Chicken))
Novartis Pharma Research

Curated by ChEMBL
LigandPNGBDBM50097944(3-[4-Amino-5-(3-methoxy-phenyl)-pyrrolo[2,3-d]pyri...)copy SMILEScopy InChI
Affinity DataIC50: 20nMAssay Description:Inhibition of p60 c-Src tyrosine kinase activityMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2FF3RMFPubMed
TargetTyrosine-protein kinase ABL1/ABL2(Homo sapiens (Human))
Novartis Pharma Research

Curated by ChEMBL
LigandPNGBDBM50097944(3-[4-Amino-5-(3-methoxy-phenyl)-pyrrolo[2,3-d]pyri...)copy SMILEScopy InChI
Affinity DataIC50: 230nMAssay Description:Inhibition of p60 c-Src tyrosine kinase activityMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2FF3RMFPubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Novartis Pharma Research

Curated by ChEMBL
LigandPNGBDBM50097944(3-[4-Amino-5-(3-methoxy-phenyl)-pyrrolo[2,3-d]pyri...)copy SMILEScopy InChI
Affinity DataIC50: 330nMAssay Description:Inhibition of Epidermal growth factor receptor (EGF-R) tyrosine kinase activity More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2FF3RMFPubMed