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SMILES CC(C)(C)OC(=O)N1CCC(C1)n1cc(-c2cccc(O)c2)c2c(N)ncnc12

InChI Key InChIKey=DDCRNOXQNBDLGB-UHFFFAOYSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50097968   

TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Novartis Pharma Research

Curated by ChEMBL
LigandPNGBDBM50097968(3-[4-Amino-5-(3-hydroxy-phenyl)-pyrrolo[2,3-d]pyri...)copy SMILEScopy InChI
Affinity DataIC50: 5nMAssay Description:Inhibition of p60 c-Src tyrosine kinase enzyme activity in liquid-phase tyrosine phosphorylation assay at 830 ng/mLMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q29P30XJPubMed
TargetProto-oncogene tyrosine-protein kinase Src(Gallus gallus (Chicken))
Novartis Pharma Research

Curated by ChEMBL
LigandPNGBDBM50097968(3-[4-Amino-5-(3-hydroxy-phenyl)-pyrrolo[2,3-d]pyri...)copy SMILEScopy InChI
Affinity DataIC50: 3.10E+3nMAssay Description:Concentration required for inhibition of c-Src mediated phosphorylation of Fak in IC8.1 fibroblast cell assayMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q29P30XJPubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Novartis Pharma Research

Curated by ChEMBL
LigandPNGBDBM50097968(3-[4-Amino-5-(3-hydroxy-phenyl)-pyrrolo[2,3-d]pyri...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+4nMAssay Description:Concentration required for inhibition of v-Abl receptor by tyrosine kinase enzyme assayMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q29P30XJPubMed
TargetTyrosine-protein kinase ABL1/ABL2(Homo sapiens (Human))
Novartis Pharma Research

Curated by ChEMBL
LigandPNGBDBM50097968(3-[4-Amino-5-(3-hydroxy-phenyl)-pyrrolo[2,3-d]pyri...)copy SMILEScopy InChI
Affinity DataIC50: 58nMAssay Description:Concentration required for inhibition of v-Abl receptor by tyrosine kinase enzyme assayMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q29P30XJPubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Novartis Pharma Research

Curated by ChEMBL
LigandPNGBDBM50097968(3-[4-Amino-5-(3-hydroxy-phenyl)-pyrrolo[2,3-d]pyri...)copy SMILEScopy InChI
Affinity DataIC50: 2.20E+3nMAssay Description:Concentration required for inhibition of epidermal growth factor receptor (EGF-R) by tyrosine kinase enzyme activityMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q29P30XJPubMed