null

SMILES CNC(=O)[C@H](Cc1ccc(OC)cc1)NC(=O)[C@H](CC(C)C)CC(=O)NO

InChI Key InChIKey=QYZPDCGWIJYZMN-ZBFHGGJFSA-N

PDB links: 1 PDB ID matches this monomer.

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 14 hits for monomerid = 50104969   

TargetNeutrophil collagenase(Human)
The DuPont Pharmaceuticals Company

Curated by ChEMBL
LigandPNGBDBM50104969((R)-N*4*-Hydroxy-2-isobutyl-N*1*-[(S)-2-(4-methoxy...)copy SMILEScopy InChI
Affinity DataKi:  0.700nMAssay Description:Inhibition of matrix metalloprotease-8More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2057F7HPubMed
Target72 kDa type IV collagenase(Human)
The DuPont Pharmaceuticals Company

Curated by ChEMBL
LigandPNGBDBM50104969((R)-N*4*-Hydroxy-2-isobutyl-N*1*-[(S)-2-(4-methoxy...)copy SMILEScopy InChI
Affinity DataKi: <1nMAssay Description:Inhibition of matrix metalloprotease-2More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2057F7HPubMed
TargetMatrix metalloproteinase-9(Human)
The DuPont Pharmaceuticals Company

Curated by ChEMBL
LigandPNGBDBM50104969((R)-N*4*-Hydroxy-2-isobutyl-N*1*-[(S)-2-(4-methoxy...)copy SMILEScopy InChI
Affinity DataKi: <1nMAssay Description:Inhibition of human matrix metalloprotease-9More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2057F7HPubMed
TargetInterstitial collagenase(Human)
The DuPont Pharmaceuticals Company

Curated by ChEMBL
LigandPNGBDBM50104969((R)-N*4*-Hydroxy-2-isobutyl-N*1*-[(S)-2-(4-methoxy...)copy SMILEScopy InChI
Affinity DataKi: <1nMAssay Description:Inhibition of matrix metalloprotease-1More data for this Ligand-Target Pair
TargetInterstitial collagenase(Human)
The DuPont Pharmaceuticals Company

Curated by ChEMBL
LigandPNGBDBM50104969((R)-N*4*-Hydroxy-2-isobutyl-N*1*-[(S)-2-(4-methoxy...)copy SMILEScopy InChI
Affinity DataKi:  6nMAssay Description:Evaluated for inhibitory activity against Human fidroblast collagenase (HFC)More data for this Ligand-Target Pair
TargetInterstitial collagenase(Human)
The DuPont Pharmaceuticals Company

Curated by ChEMBL
LigandPNGBDBM50104969((R)-N*4*-Hydroxy-2-isobutyl-N*1*-[(S)-2-(4-methoxy...)copy SMILEScopy InChI
Affinity DataKi: <10nMAssay Description:Inhibition of Matrix metalloproteinase-1 (MMP-1)More data for this Ligand-Target Pair
Target72 kDa type IV collagenase(Human)
The DuPont Pharmaceuticals Company

Curated by ChEMBL
LigandPNGBDBM50104969((R)-N*4*-Hydroxy-2-isobutyl-N*1*-[(S)-2-(4-methoxy...)copy SMILEScopy InChI
Affinity DataKi: <10nMAssay Description:Inhibition of Matrix metalloproteinase-2 (MMP-2)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TH8MQ4
TargetStromelysin-1(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50104969((R)-N*4*-Hydroxy-2-isobutyl-N*1*-[(S)-2-(4-methoxy...)copy SMILEScopy InChI
Affinity DataKi: <10nMAssay Description:Inhibition of Matrix metalloproteinase-3 (MMP-3)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TH8MQ4
TargetMatrix metalloproteinase-9(Human)
The DuPont Pharmaceuticals Company

Curated by ChEMBL
LigandPNGBDBM50104969((R)-N*4*-Hydroxy-2-isobutyl-N*1*-[(S)-2-(4-methoxy...)copy SMILEScopy InChI
Affinity DataKi: <10nMAssay Description:Inhibition of Matrix metalloproteinase-9More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TH8MQ4
TargetMatrilysin(Human)
Pfizer Global Research and Development

Curated by ChEMBL
LigandPNGBDBM50104969((R)-N*4*-Hydroxy-2-isobutyl-N*1*-[(S)-2-(4-methoxy...)copy SMILEScopy InChI
Affinity DataIC50: 30nMAssay Description:Inhibition of human matrix metalloprotease-7 (MMP-7)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24F1Q3RPubMed
TargetInterstitial collagenase(Human)
The DuPont Pharmaceuticals Company

Curated by ChEMBL
LigandPNGBDBM50104969((R)-N*4*-Hydroxy-2-isobutyl-N*1*-[(S)-2-(4-methoxy...)copy SMILEScopy InChI
Affinity DataIC50: 20nMAssay Description:Inhibition of human Matrix metalloprotease-1 (MMP-1)More data for this Ligand-Target Pair
TargetInterstitial collagenase(Human)
The DuPont Pharmaceuticals Company

Curated by ChEMBL
LigandPNGBDBM50104969((R)-N*4*-Hydroxy-2-isobutyl-N*1*-[(S)-2-(4-methoxy...)copy SMILEScopy InChI
Affinity DataIC50: 1.90nMAssay Description:Inhibition of Matrix Metallo Proteinase-1(MMP-1)More data for this Ligand-Target Pair
Target72 kDa type IV collagenase(Human)
The DuPont Pharmaceuticals Company

Curated by ChEMBL
LigandPNGBDBM50104969((R)-N*4*-Hydroxy-2-isobutyl-N*1*-[(S)-2-(4-methoxy...)copy SMILEScopy InChI
Affinity DataIC50: 6nMAssay Description:Inhibition of human matrix metalloprotease-2 (MMP-2)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24F1Q3RPubMed
TargetStromelysin-1(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50104969((R)-N*4*-Hydroxy-2-isobutyl-N*1*-[(S)-2-(4-methoxy...)copy SMILEScopy InChI
Affinity DataIC50: 30nMAssay Description:Inhibition of human matrix metalloprotease-3 (MMP-3)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24F1Q3RPubMed