null

SMILES NC(=O)CNC(=O)[C@@H]1CCCCNC(=O)OCCC[C@@H]([C@@H](Cc2ccc(cc2)-c2ccccc2C(F)(F)F)C(=O)N1)C(=O)NO

InChI Key InChIKey=SOPDPCOBVSOXIM-ZDXQCDESSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 13 hits for monomerid = 50104974   

TargetDisintegrin and metalloproteinase domain-containing protein 17(Sus scrofa (pig))
DuPont Pharmaceuticals Company

Curated by ChEMBL
LigandPNGBDBM50104974(2,10-Dioxo-11-(2'-trifluoromethyl-biphenyl-4-ylmet...)copy SMILEScopy InChI
Affinity DataKi:  1.5nMAssay Description:Inhibition of porcine TNF-alpha converting enzyme(pTACE).More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2VD6XRTPubMed
TargetNeutrophil collagenase(Homo sapiens (Human))
DuPont Pharmaceuticals Company

Curated by ChEMBL
LigandPNGBDBM50104974(2,10-Dioxo-11-(2'-trifluoromethyl-biphenyl-4-ylmet...)copy SMILEScopy InChI
Affinity DataKi:  428nMAssay Description:Inhibition of matrix metalloprotease-8More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2VD6XRTPubMed
TargetCollagenase 3(Homo sapiens (Human))
DuPont Pharmaceuticals Company

Curated by ChEMBL
LigandPNGBDBM50104974(2,10-Dioxo-11-(2'-trifluoromethyl-biphenyl-4-ylmet...)copy SMILEScopy InChI
Affinity DataKi:  442nMAssay Description:Inhibition of matrix metalloprotease-13More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2VD6XRTPubMed
TargetMatrilysin(Homo sapiens (Human))
DuPont Pharmaceuticals Company

Curated by ChEMBL
LigandPNGBDBM50104974(2,10-Dioxo-11-(2'-trifluoromethyl-biphenyl-4-ylmet...)copy SMILEScopy InChI
Affinity DataKi:  1.34E+3nMAssay Description:Inhibition of matrix metalloprotease-7More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2VD6XRTPubMed
Target72 kDa type IV collagenase(Homo sapiens (Human))
DuPont Pharmaceuticals Company

Curated by ChEMBL
LigandPNGBDBM50104974(2,10-Dioxo-11-(2'-trifluoromethyl-biphenyl-4-ylmet...)copy SMILEScopy InChI
Affinity DataKi:  1.87E+3nMAssay Description:Inhibition of matrix metalloprotease-2More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2VD6XRTPubMed
TargetInterstitial collagenase(Homo sapiens (Human))
DuPont Pharmaceuticals Company

Curated by ChEMBL
LigandPNGBDBM50104974(2,10-Dioxo-11-(2'-trifluoromethyl-biphenyl-4-ylmet...)copy SMILEScopy InChI
Affinity DataKi: >2.00E+3nMAssay Description:Inhibition of matrix metalloprotease-1More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2VD6XRTPubMed
TargetStromelysin-1(Homo sapiens (Human))
DuPont Pharmaceuticals Company

Curated by ChEMBL
LigandPNGBDBM50104974(2,10-Dioxo-11-(2'-trifluoromethyl-biphenyl-4-ylmet...)copy SMILEScopy InChI
Affinity DataKi: >2.00E+3nMAssay Description:Inhibition of matrix metalloprotease-3More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2VD6XRTPubMed
TargetStromelysin-2(Homo sapiens (Human))
DuPont Pharmaceuticals Company

Curated by ChEMBL
LigandPNGBDBM50104974(2,10-Dioxo-11-(2'-trifluoromethyl-biphenyl-4-ylmet...)copy SMILEScopy InChI
Affinity DataKi: >2.00E+3nMAssay Description:Inhibition of matrix metalloprotease-10More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2VD6XRTPubMed
TargetMatrix metalloproteinase-9(Homo sapiens (Human))
DuPont Pharmaceuticals Company

Curated by ChEMBL
LigandPNGBDBM50104974(2,10-Dioxo-11-(2'-trifluoromethyl-biphenyl-4-ylmet...)copy SMILEScopy InChI
Affinity DataKi: >2.00E+3nMAssay Description:Inhibition of human matrix metalloprotease-9More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2VD6XRTPubMed
TargetMatrix metalloproteinase-14(Homo sapiens (Human))
DuPont Pharmaceuticals Company

Curated by ChEMBL
LigandPNGBDBM50104974(2,10-Dioxo-11-(2'-trifluoromethyl-biphenyl-4-ylmet...)copy SMILEScopy InChI
Affinity DataKi: >2.00E+3nMAssay Description:Inhibition of matrix metalloprotease-14More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2VD6XRTPubMed
TargetMatrix metalloproteinase-16(Homo sapiens (Human))
DuPont Pharmaceuticals Company

Curated by ChEMBL
LigandPNGBDBM50104974(2,10-Dioxo-11-(2'-trifluoromethyl-biphenyl-4-ylmet...)copy SMILEScopy InChI
Affinity DataKi: >2.00E+3nMAssay Description:Inhibition of matrix metalloprotease-16More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2VD6XRTPubMed
TargetMacrophage metalloelastase(Homo sapiens (Human))
DuPont Pharmaceuticals Company

Curated by ChEMBL
LigandPNGBDBM50104974(2,10-Dioxo-11-(2'-trifluoromethyl-biphenyl-4-ylmet...)copy SMILEScopy InChI
Affinity DataKi: >2.00E+3nMAssay Description:Inhibition of matrix metalloprotease-12More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2VD6XRTPubMed
TargetMatrix metalloproteinase-15(Homo sapiens (Human))
DuPont Pharmaceuticals Company

Curated by ChEMBL
LigandPNGBDBM50104974(2,10-Dioxo-11-(2'-trifluoromethyl-biphenyl-4-ylmet...)copy SMILEScopy InChI
Affinity DataKi: >2.00E+3nMAssay Description:Inhibition of matrix metalloprotease-15More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2VD6XRTPubMed