null

SMILES OC(=O)CCNC(=O)CNC(=O)CCCc1ccc2CCCNc2n1

InChI Key InChIKey=PTMCXHYHUJMORP-UHFFFAOYSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50107405   

TargetIntegrin alpha-V/beta-3(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50107405(3-[2-(4-5,6,7,8-Tetrahydro-[1,8]naphthyridin-2-yl-...)copy SMILEScopy InChI
Affinity DataIC50: 111nMAssay Description:Inhibition of Vitronectin receptor, integrin alphaV-beta3 expressed in HEK 293 cellsMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2VM4BKVPubMed
TargetIntegrin alpha-IIb/beta-3(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50107405(3-[2-(4-5,6,7,8-Tetrahydro-[1,8]naphthyridin-2-yl-...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of integrin alphaIIb-beta3 in platelet aggregation assayMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2VM4BKVPubMed
TargetIntegrin alpha-V/beta-3(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50107405(3-[2-(4-5,6,7,8-Tetrahydro-[1,8]naphthyridin-2-yl-...)copy SMILEScopy InChI
Affinity DataIC50: 111nMAssay Description:Displacement of a non-peptide radioligand from human recombinant alphaV-beta3 integrinMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q289171XPubMed
TargetIntegrin alpha-IIb/beta-3(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50107405(3-[2-(4-5,6,7,8-Tetrahydro-[1,8]naphthyridin-2-yl-...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+4nMAssay Description:Displacement of a non-peptide radioligand from human recombinant alphaV-beta3 integrinMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q289171XPubMed
TargetIntegrin alpha-V/beta-3(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50107405(3-[2-(4-5,6,7,8-Tetrahydro-[1,8]naphthyridin-2-yl-...)copy SMILEScopy InChI
Affinity DataIC50: 48nMAssay Description:Inhibition of binding to human alpha V beta3More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2MK6F2MPubMed