null

SMILES C[C@H]1[C@@H]2[C@H](CCN2C(=O)[C@@H]2CCCN2S(=O)(=O)c2cccc3c(cccc23)N(C)C)N(C(=O)C2CC2)C1=O

InChI Key InChIKey=VSHOGRNAHIXNQF-XVYJZYCRSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50107904   

TargetCapsid scaffolding protein(Human cytomegalovirus (strain AD169) (HHV-5) (Huma...)
GlaxoSmithKline Research and Development

Curated by ChEMBL
LigandPNGBDBM50107904((3S,3aR,6aS)-1-Cyclopropanecarbonyl-4-[(S)-1-(5-di...)copy SMILEScopy InChI
Affinity DataKi:  20nMAssay Description:Potency against human cytomegalovirus protease in HCMV pNA assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2WH2PD8PubMed
TargetGenome polyprotein(Human rhinovirus B)
GlaxoSmithKline Research and Development

Curated by ChEMBL
LigandPNGBDBM50107904((3S,3aR,6aS)-1-Cyclopropanecarbonyl-4-[(S)-1-(5-di...)copy SMILEScopy InChI
Affinity DataKi:  20nMAssay Description:Binding affinity towards Human cytomegalovirus (HCMV) proteaseMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2Q52NZ1PubMed
TargetCapsid scaffolding protein(Human cytomegalovirus (strain AD169) (HHV-5) (Huma...)
GlaxoSmithKline Research and Development

Curated by ChEMBL
LigandPNGBDBM50107904((3S,3aR,6aS)-1-Cyclopropanecarbonyl-4-[(S)-1-(5-di...)copy SMILEScopy InChI
Affinity DataIC50: 340nMAssay Description:Concentration required for inhibition of human cytomegalo virus (HCMV) protease activity.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2Q52NZ1PubMed
TargetCapsid scaffolding protein(Human cytomegalovirus (strain AD169) (HHV-5) (Huma...)
GlaxoSmithKline Research and Development

Curated by ChEMBL
LigandPNGBDBM50107904((3S,3aR,6aS)-1-Cyclopropanecarbonyl-4-[(S)-1-(5-di...)copy SMILEScopy InChI
Affinity DataIC50: 340nMAssay Description:Tested in vitro for inhibitory activity of the compound against ProteaseMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q22F7MRPPubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
GlaxoSmithKline Research and Development

Curated by ChEMBL
LigandPNGBDBM50107904((3S,3aR,6aS)-1-Cyclopropanecarbonyl-4-[(S)-1-(5-di...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+5nMAssay Description:Concentration required for 50% Acetylcholinesterase inhibitionMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2Q52NZ1PubMed
TargetCapsid scaffolding protein(Human cytomegalovirus (strain AD169) (HHV-5) (Huma...)
GlaxoSmithKline Research and Development

Curated by ChEMBL
LigandPNGBDBM50107904((3S,3aR,6aS)-1-Cyclopropanecarbonyl-4-[(S)-1-(5-di...)copy SMILEScopy InChI
Affinity DataIC50: 340nMAssay Description:Inhibition of human cytomegalovirus protease in HCMV pNA assay.More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2WH2PD8PubMed
TargetProthrombin(Homo sapiens (Human))
GlaxoSmithKline Research and Development

Curated by ChEMBL
LigandPNGBDBM50107904((3S,3aR,6aS)-1-Cyclopropanecarbonyl-4-[(S)-1-(5-di...)copy SMILEScopy InChI
Affinity DataIC50: 2.00E+5nMAssay Description:Concentration required for 50% thrombin inhibitionMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2Q52NZ1PubMed