null

SMILES CCOP(=O)(N1CCN(CC1C(=O)NO)C(=O)OCc1ccccc1)c1ccc(OC)cc1

InChI Key InChIKey=LXKHXLQQHKRMFP-UHFFFAOYSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50109637   

TargetMatrix metalloproteinase-9(Homo sapiens (Human))
Nippon Organon K.K.

Curated by ChEMBL
LigandPNGBDBM50109637(4-[Ethoxy-(4-methoxy-phenyl)-phosphinoyl]-3-hydrox...)copy SMILEScopy InChI
Affinity DataKi:  5.20nMAssay Description:Inhibitory activity against matrix metalloprotease-9 (MMP-9)(gelatinase-B).More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2XK8G9QPubMed
TargetDisintegrin and metalloproteinase domain-containing protein 17(Homo sapiens (Human))
Nippon Organon K.K.

Curated by ChEMBL
LigandPNGBDBM50109637(4-[Ethoxy-(4-methoxy-phenyl)-phosphinoyl]-3-hydrox...)copy SMILEScopy InChI
Affinity DataKi:  7.99nMAssay Description:Inhibitory activity against tumor necrosis factor alpha converting enzyme (TACE) from human acute monocytic leukemia cell line.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2XK8G9QPubMed
TargetStromelysin-1(Homo sapiens (Human))
Nippon Organon K.K.

Curated by ChEMBL
LigandPNGBDBM50109637(4-[Ethoxy-(4-methoxy-phenyl)-phosphinoyl]-3-hydrox...)copy SMILEScopy InChI
Affinity DataKi:  14.9nMAssay Description:Inhibitory activity against matrix metalloprotease-3 (MMP-3)(stromelysin-1).More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2XK8G9QPubMed
TargetInterstitial collagenase(Homo sapiens (Human))
Nippon Organon K.K.

Curated by ChEMBL
LigandPNGBDBM50109637(4-[Ethoxy-(4-methoxy-phenyl)-phosphinoyl]-3-hydrox...)copy SMILEScopy InChI
Affinity DataKi:  20.1nMAssay Description:Inhibitory activity against matrix metalloprotease-1 (MMP-1)(recombinant human collagenase-1).More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2XK8G9QPubMed
TargetDisintegrin and metalloproteinase domain-containing protein 9(Homo sapiens (Human))
Nippon Organon K.K.

Curated by ChEMBL
LigandPNGBDBM50109637(4-[Ethoxy-(4-methoxy-phenyl)-phosphinoyl]-3-hydrox...)copy SMILEScopy InChI
Affinity DataIC50: 430nMAssay Description:Inhibition of the heparin binding epidermal growth factor (HB-EGF) release from fibrosarcoma HT1080 transfectants expressing alkaline phosphate (AP) ...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2XK8G9QPubMed