null

SMILES CN1CCN(CC1)c1cc(Nc2cc(C)[nH]n2)nc(Oc2cccc(NC(=O)C=C)c2)n1

InChI Key InChIKey=PSWJMRDJPWAQDI-UHFFFAOYSA-N

PDB links: 1 PDB ID matches this monomer.

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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50111472   

TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
TU Dortmund University

Curated by ChEMBL
LigandPNGBDBM50111472(CHEMBL3604921)copy SMILEScopy InChI
Affinity DataIC50: 170nMAssay Description:Inhibition of cSrc T338M mutant (unknown origin) pre-incubated for 30 mins before substrate and ATP addition by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2WM1G59PubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
TU Dortmund University

Curated by ChEMBL
LigandPNGBDBM50111472(CHEMBL3604921)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of wild type EGFR (unknown origin) expressed in Sf9 cells pre-incubated for 30 mins before substrate and ATP addition by homogeneous time-...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2WM1G59PubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
TU Dortmund University

Curated by ChEMBL
LigandPNGBDBM50111472(CHEMBL3604921)copy SMILEScopy InChI
Affinity DataIC50: 28nMAssay Description:Inhibition of cSrc T338M/S345C mutant (unknown origin) pre-incubated for 30 mins before substrate and ATP addition by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2WM1G59PubMed