null

SMILES OC1(N2CCN=C2c2ccccc12)c1ccc2ccccc2c1

InChI Key InChIKey=RKCUTIXVCFBEGE-UHFFFAOYSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50118291   

TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Drew University

Curated by ChEMBL
LigandPNGBDBM50118291(5-Naphthalen-2-yl-2,5-dihydro-3H-imidazo[2,1-a]iso...)copy SMILEScopy InChI
Affinity DataKi:  2.30nMAssay Description:Inhibition of [125I]- RTI -55 binding at the Serotonin transporter sites on HEK-hSERT cellsMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q25Q4VF3PubMed
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Drew University

Curated by ChEMBL
LigandPNGBDBM50118291(5-Naphthalen-2-yl-2,5-dihydro-3H-imidazo[2,1-a]iso...)copy SMILEScopy InChI
Affinity DataKi:  11nMAssay Description:Inhibition of [125I]- RTI -55 binding at the Norepinephrin transpoter sites on HEK-hNET cellsMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q25Q4VF3PubMed
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Drew University

Curated by ChEMBL
LigandPNGBDBM50118291(5-Naphthalen-2-yl-2,5-dihydro-3H-imidazo[2,1-a]iso...)copy SMILEScopy InChI
Affinity DataKi:  45nMAssay Description:Inhibition of [125I]- RTI -55 binding at the Dopamine transporter sites on HEK-hDAT cellsMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q25Q4VF3PubMed
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
National Institute on Drug Abuse-Intramural Research Program/NIH

Curated by ChEMBL
LigandPNGBDBM50118291(5-Naphthalen-2-yl-2,5-dihydro-3H-imidazo[2,1-a]iso...)copy SMILEScopy InChI
Affinity DataIC50: 23nMAssay Description:Ability to displace [3H]-WIN-35,428 from dopamine transporter in rat caudate putamen tissueMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q21Z43R6PubMed
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
National Institute on Drug Abuse-Intramural Research Program/NIH

Curated by ChEMBL
LigandPNGBDBM50118291(5-Naphthalen-2-yl-2,5-dihydro-3H-imidazo[2,1-a]iso...)copy SMILEScopy InChI
Affinity DataIC50: 23.3nMAssay Description:Ability to displace [3H]- WIN 35,428 from dopamine transporter on rat striatal membrane.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q25Q4VF3PubMed
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Drew University

Curated by ChEMBL
LigandPNGBDBM50118291(5-Naphthalen-2-yl-2,5-dihydro-3H-imidazo[2,1-a]iso...)copy SMILEScopy InChI
Affinity DataIC50: 4.10nMAssay Description:Ability to displace [3H]- WIN 35,428 from dopamine transporter on guinea pig striatal membrane.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q25Q4VF3PubMed