null

SMILES CCc1cc(Oc2cccc(c2)N(C[C@@H](O)C(F)(F)F)Cc2cccc(OC(F)(F)C(F)F)c2)ccc1Cl

InChI Key InChIKey=VHSPKQAESIGBIC-HSZRJFAPSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50128131   

TargetCholesteryl ester transfer protein(Homo sapiens (Human))
Pharmacia Discovery Research (Pfizer Global Research and Development)

Curated by ChEMBL
LigandPNGBDBM50128131((R)-3-((3-(1,1,2,2-tetrafluoroethoxy)benzyl)(3-(4-...)copy SMILEScopy InChI
Affinity DataIC50: 73nMAssay Description:Compound was tested in vitro for inhibitory activity against recombinant human cholesteryl ester transfer protein in hamster serumMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QV3KWKPubMed
TargetCholesteryl ester transfer protein(Homo sapiens (Human))
Pharmacia Discovery Research (Pfizer Global Research and Development)

Curated by ChEMBL
LigandPNGBDBM50128131((R)-3-((3-(1,1,2,2-tetrafluoroethoxy)benzyl)(3-(4-...)copy SMILEScopy InChI
Affinity DataIC50: 3.00E+3nMAssay Description:Compound was tested in vitro for inhibitory activity against recombinant human cholesteryl ester transfer protein in bufferMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QV3KWKPubMed
TargetCholesteryl ester transfer protein(Oryctolagus cuniculus)
Al-Zaytoonah Private University of Jordan

Curated by ChEMBL
LigandPNGBDBM50128131((R)-3-((3-(1,1,2,2-tetrafluoroethoxy)benzyl)(3-(4-...)copy SMILEScopy InChI
Affinity DataIC50: 4nMAssay Description:Inhibition of CETP in rabbit serum after 1 hr by fluorescent cholesteryl esters transfer assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2VQ32VSPubMed
TargetCholesteryl ester transfer protein(Homo sapiens (Human))
Pharmacia Discovery Research (Pfizer Global Research and Development)

Curated by ChEMBL
LigandPNGBDBM50128131((R)-3-((3-(1,1,2,2-tetrafluoroethoxy)benzyl)(3-(4-...)copy SMILEScopy InChI
Affinity DataIC50: 5.90E+4nMAssay Description:Compound was tested in vitro for inhibitory activity against recombinant human cholesteryl ester transfer protein in human serumMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QV3KWKPubMed
TargetCholesteryl ester transfer protein(Homo sapiens (Human))
Pharmacia Discovery Research (Pfizer Global Research and Development)

Curated by ChEMBL
LigandPNGBDBM50128131((R)-3-((3-(1,1,2,2-tetrafluoroethoxy)benzyl)(3-(4-...)copy SMILEScopy InChI
Affinity DataIC50: 0.770nMAssay Description:Compound was tested in vitro for inhibitory activity against recombinant human cholesteryl ester transfer protein in buffer with <1 nM [CETP] for 18 ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QV3KWKPubMed
TargetCholesteryl ester transfer protein(Homo sapiens (Human))
Pharmacia Discovery Research (Pfizer Global Research and Development)

Curated by ChEMBL
LigandPNGBDBM50128131((R)-3-((3-(1,1,2,2-tetrafluoroethoxy)benzyl)(3-(4-...)copy SMILEScopy InChI
Affinity DataIC50: 80nMAssay Description:Compound was tested in vitro for inhibitory activity against recombinant human cholesteryl ester transfer protein in rabbit serumMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QV3KWKPubMed