null
SMILES CS(=O)(=O)Nc1ccccc1N1CCN(CC1)C(=O)[C@@H](Cc1ccc(Cl)cc1)NC(=O)[C@H]1Cc2ccccc2CN1
InChI Key InChIKey=DOQXGQVRPIRXJG-KAYWLYCHSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 7 hits for monomerid = 50134496
Affinity DataKi: 220nMAssay Description:Binding affinity towards human melanocortin 4 receptor using [125I]NDP-alpha-MSH as a radioligand in HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 1.20E+3nMAssay Description:Binding affinity towards human Melanocortin 5 receptor (MC5R) using [125I]NDP-alpha-MSH as a radioligand in membranes of HEK 293 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 8.80E+3nMAssay Description:Binding affinity towards human Melanocortin 3 receptor (MC3R) using [125I]NDP-alpha-MSH as a radioligand in membranes of HEK 293 cellsMore data for this Ligand-Target Pair
TargetMelanocyte-stimulating hormone receptor(Homo sapiens (Human))
Lilly Research Laboratories
Curated by ChEMBL
Lilly Research Laboratories
Curated by ChEMBL
Affinity DataKi: 1.20E+4nMAssay Description:Binding affinity towards human Melanocortin 1 receptor (MC1R) using [125I]NDP-alpha-MSH as a radioligand in membranes of HEK 293 cellsMore data for this Ligand-Target Pair
Affinity DataEC50: 380nMAssay Description:Agonistic activity measured as inhibition of cAMP accumulation in HEK cells expressing human Melanocortin 4 receptor (hMC4R)More data for this Ligand-Target Pair
Affinity DataEC50: 16nMAssay Description:Agonistic potency of the compound towards human melanocortin 4 receptor, determined by 50% maximum cAMP releaseMore data for this Ligand-Target Pair
Affinity DataEC50: 2.00E+3nMAssay Description:Agonistic potency of the compound towards human Melanocortin 3 receptor (MC3R) was determined by 50% maximum cAMP releaseMore data for this Ligand-Target Pair