null

SMILES NC(=O)N(O)CCC#Cc1ccc(CN2CCN(CC2)[C@H](c2ccccc2)c2ccc(Cl)cc2)o1

InChI Key InChIKey=GLXQEUGDWMYWCC-AREMUKBSSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50144625   

TargetHistamine H1 receptor(Homo sapiens (Human))
UCB Research

Curated by ChEMBL
LigandPNGBDBM50144625(1-[4-(5-{4-[(R)-(4-Chloro-phenyl)-phenyl-methyl]-p...)copy SMILEScopy InChI
Affinity DataKi:  150nMAssay Description:In vitro binding affinity towards histamine H1 receptor expressed in CHO-K1 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2BV7G2PPubMed
TargetHistamine H1 receptor(Homo sapiens (Human))
UCB Research

Curated by ChEMBL
LigandPNGBDBM50144625(1-[4-(5-{4-[(R)-(4-Chloro-phenyl)-phenyl-methyl]-p...)copy SMILEScopy InChI
Affinity DataKi:  150nMAssay Description:Inhibition constant against histamine H1 receptorMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2SF2WZ9PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
Organon Laboratories

Curated by ChEMBL
LigandPNGBDBM50144625(1-[4-(5-{4-[(R)-(4-Chloro-phenyl)-phenyl-methyl]-p...)copy SMILEScopy InChI
Affinity DataIC50: 420nMAssay Description:Inhibition constant against arachidonate 5-lipoxygenase More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2SF2WZ9PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
Organon Laboratories

Curated by ChEMBL
LigandPNGBDBM50144625(1-[4-(5-{4-[(R)-(4-Chloro-phenyl)-phenyl-methyl]-p...)copy SMILEScopy InChI
Affinity DataIC50: 420nMAssay Description:In vitro inhibitory activity against 5-lipoxygenase in a human whole blood assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2BV7G2PPubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Rattus norvegicus)
UCB Research

Curated by ChEMBL
LigandPNGBDBM50144625(1-[4-(5-{4-[(R)-(4-Chloro-phenyl)-phenyl-methyl]-p...)copy SMILEScopy InChI
Affinity DataIC50: 200nMAssay Description:In vitro inhibitory activity against 5-lipoxygenase in an RBL-2H3 cell lysateMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2BV7G2PPubMed