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SMILES [H][C@@]12CCC[C@]1([H])N1C(=N2)N(C)C(=O)c2c(Nc3ccccc3)n(Cc3ccc(cc3)-c3ccccn3)nc12
InChI Key InChIKey=RJKWLGFYXTZMOU-RPWUZVMVSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 9 hits for monomerid = 50150264
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A(Homo sapiens (Human))
Intra-Cellular Therapies, Inc.
Curated by ChEMBL
Intra-Cellular Therapies, Inc.
Curated by ChEMBL
Affinity DataKi: 240nMAssay Description:Inhibition of recombinant full lenght human PDE4A using fluorescent labeled cAMP as substrate after 15 mins by IMAP assayMore data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 7B(Homo sapiens (Human))
Intra-Cellular Therapies, Inc.
Curated by ChEMBL
Intra-Cellular Therapies, Inc.
Curated by ChEMBL
Affinity DataKi: 300nMAssay Description:Inhibition of recombinant full lenght human PDE7B using fluorescent labeled cAMP as substrate after 15 mins by IMAP assayMore data for this Ligand-Target Pair
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Intra-Cellular Therapies, Inc.
Curated by ChEMBL
Intra-Cellular Therapies, Inc.
Curated by ChEMBL
Affinity DataKi: 600nMAssay Description:Inhibition of recombinant full lenght human PDE5A using fluorescent labeled cGMP as substrate after 15 mins by IMAP assayMore data for this Ligand-Target Pair
TargetcGMP-inhibited 3',5'-cyclic phosphodiesterase 3B(Homo sapiens (Human))
Intra-Cellular Therapies, Inc.
Curated by ChEMBL
Intra-Cellular Therapies, Inc.
Curated by ChEMBL
Affinity DataKi: 1.20E+3nMAssay Description:Inhibition of recombinant full length human PDE3B using fluorescent labeled cAMP as substrate after 15 mins by IMAP assayMore data for this Ligand-Target Pair
TargetDual 3',5'-cyclic-AMP and -GMP phosphodiesterase 11A(Homo sapiens (Human))
Intra-Cellular Therapies, Inc.
Curated by ChEMBL
Intra-Cellular Therapies, Inc.
Curated by ChEMBL
Affinity DataKi: 2.60E+3nMAssay Description:Inhibition of recombinant full lenght human PDE11A using fluorescent labeled cAMP as substrate after 15 mins by IMAP assayMore data for this Ligand-Target Pair
TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Homo sapiens (Human))
Intra-Cellular Therapies, Inc.
Curated by ChEMBL
Intra-Cellular Therapies, Inc.
Curated by ChEMBL
Affinity DataKi: 2.70E+3nMAssay Description:Inhibition of recombinant full lenght human PDE10A using fluorescent labeled cAMP as substrate after 15 mins by IMAP assayMore data for this Ligand-Target Pair
TargetHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A(Homo sapiens (Human))
Intra-Cellular Therapies, Inc.
Curated by ChEMBL
Intra-Cellular Therapies, Inc.
Curated by ChEMBL
Affinity DataKi: 6.10E+3nMAssay Description:Inhibition of recombinant full lenght human PDE9A using fluorescent labeled cGMP as substrate after 15 mins by IMAP assayMore data for this Ligand-Target Pair
TargetHigh affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8A(Homo sapiens (Human))
Intra-Cellular Therapies, Inc.
Curated by ChEMBL
Intra-Cellular Therapies, Inc.
Curated by ChEMBL
Affinity DataKi: 8.20E+3nMAssay Description:Inhibition of recombinant full lenght human PDE8A using fluorescent labeled cAMP as substrate after 15 mins by IMAP assayMore data for this Ligand-Target Pair
TargetcGMP-dependent 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Intra-Cellular Therapies, Inc.
Curated by ChEMBL
Intra-Cellular Therapies, Inc.
Curated by ChEMBL
Affinity DataKi: 2.40E+4nMAssay Description:Inhibition of recombinant full length human PDE2A using fluorescent labeled cAMP as substrate after 15 mins by IMAP assayMore data for this Ligand-Target Pair