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SMILES C[C@]1(Cn2ccnn2)[C@@H](N2[C@@H](CC2=O)S1(=O)=O)C(=O)O[Na]

InChI Key InChIKey=RFMIKMMOLPNEDG-QVUDESDKSA-M

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 22 hits for monomerid = 50157692   

TargetBeta-lactamase(Escherichia coli)
MEIJI SEIKA PHARMA CO., LTD.

US Patent
LigandPNGBDBM50157692(CHEMBL1439 | CL-307579 | Sodium; (2S,3S,5R)-3-meth...)copy SMILEScopy InChI
Affinity DataIC50: 950nMpH: 7.0Assay Description:For the measurement of β-lactamase inhibitory activity, 100 μM (final concentration) nitrocefin (Oxoid) was used as a substrate, and 2.5% D...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2KP80XXUS Patent
TargetBeta-lactamase(Enterobacter cloacae)
Southern Methodist University

Curated by ChEMBL
LigandPNGBDBM50157692(CHEMBL1439 | CL-307579 | Sodium; (2S,3S,5R)-3-meth...)copy SMILEScopy InChI
Affinity DataIC50: 3.40E+3nMAssay Description:Inhibition of class C beta-lactamase derived from Enterobacter cloacae P99More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2HQ3Z41PubMed
TargetBeta-lactamase TEM(Escherichia coli)
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50157692(CHEMBL1439 | CL-307579 | Sodium; (2S,3S,5R)-3-meth...)copy SMILEScopy InChI
Affinity DataIC50: 60nMAssay Description:Inhibitory activity of the compound against TEM-1 (class A) beta-lactamaseMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2PK0FBJPubMed
TargetBeta-lactamase(Escherichia coli)
MEIJI SEIKA PHARMA CO., LTD.

US Patent
LigandPNGBDBM50157692(CHEMBL1439 | CL-307579 | Sodium; (2S,3S,5R)-3-meth...)copy SMILEScopy InChI
Affinity DataIC50: 4.77E+4nMAssay Description:Inhibitory activity of the compound against AmpC (class C) beta-lactamaseMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2PK0FBJPubMed
TargetBeta-lactamase TEM(Escherichia coli)
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50157692(CHEMBL1439 | CL-307579 | Sodium; (2S,3S,5R)-3-meth...)copy SMILEScopy InChI
Affinity DataIC50: 60nMAssay Description:Inhibitory activity of the compound against TEM-1 (class A) beta-lactamaseMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2TB163QPubMed
TargetBeta-lactamase(Staphylococcus aureus)
Southern Methodist University

Curated by ChEMBL
LigandPNGBDBM50157692(CHEMBL1439 | CL-307579 | Sodium; (2S,3S,5R)-3-meth...)copy SMILEScopy InChI
Affinity DataIC50: 290nMAssay Description:The compound was evaluated for inhibition against Beta-lactamase TEM derived from Staphylococcus aureusMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2NG4PVBPubMed
TargetMetallo-beta-lactamase L1 type 3(Stenotrophomonas maltophilia)
Southern Methodist University

Curated by ChEMBL
LigandPNGBDBM50157692(CHEMBL1439 | CL-307579 | Sodium; (2S,3S,5R)-3-meth...)copy SMILEScopy InChI
Affinity DataIC50: 2.00E+5nMAssay Description:Beta-Lactamase Inhibition of metallo-beta-lactamase representative class B (L1) enzymeMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q22Z14ZGPubMed
TargetBeta-lactamase(Escherichia coli)
MEIJI SEIKA PHARMA CO., LTD.

US Patent
LigandPNGBDBM50157692(CHEMBL1439 | CL-307579 | Sodium; (2S,3S,5R)-3-meth...)copy SMILEScopy InChI
Affinity DataIC50: 5.32E+4nMAssay Description:Beta-Lactamase inhibitory activity against representativeclass C (P99) serine enzymeMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q22Z14ZGPubMed
TargetMetallo-beta-lactamase type 2(Bacillus cereus)
Southern Methodist University

Curated by ChEMBL
LigandPNGBDBM50157692(CHEMBL1439 | CL-307579 | Sodium; (2S,3S,5R)-3-meth...)copy SMILEScopy InChI
Affinity DataIC50: 2.00E+5nMAssay Description:Beta-Lactamase Inhibition of metallo-beta-lactamase representative class B (L1) enzymeMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q22Z14ZGPubMed
TargetBeta-lactamase(Enterobacter cloacae)
Southern Methodist University

Curated by ChEMBL
LigandPNGBDBM50157692(CHEMBL1439 | CL-307579 | Sodium; (2S,3S,5R)-3-meth...)copy SMILEScopy InChI
Affinity DataIC50: 4.00E+3nMAssay Description:The concentration of compound to inhibit Beta-lactamase was measured on Enterobacter cloacae SC 12368More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q29S1Q29PubMed
TargetBeta-lactamase(Enterobacter cloacae)
Southern Methodist University

Curated by ChEMBL
LigandPNGBDBM50157692(CHEMBL1439 | CL-307579 | Sodium; (2S,3S,5R)-3-meth...)copy SMILEScopy InChI
Affinity DataIC50: 943nMAssay Description:The concentration of compound to inhibit Beta-lactamase was measured on Enterobacter cloacae P99More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q29S1Q29PubMed
TargetBeta-lactamase TEM(Escherichia coli)
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50157692(CHEMBL1439 | CL-307579 | Sodium; (2S,3S,5R)-3-meth...)copy SMILEScopy InChI
Affinity DataIC50: 25nMAssay Description:The concentration of compound to inhibit Beta-lactamase was measured on Escherichia coli WC3310More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q29S1Q29PubMed
TargetBeta-lactamase(Enterobacter cloacae)
Southern Methodist University

Curated by ChEMBL
LigandPNGBDBM50157692(CHEMBL1439 | CL-307579 | Sodium; (2S,3S,5R)-3-meth...)copy SMILEScopy InChI
Affinity DataIC50: 5.19E+4nMAssay Description:Inhibition of Class C beta-lactamase from E. cloacae strain P99More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2NG4PVBPubMed
TargetBeta-lactamase(Staphylococcus aureus)
Southern Methodist University

Curated by ChEMBL
LigandPNGBDBM50157692(CHEMBL1439 | CL-307579 | Sodium; (2S,3S,5R)-3-meth...)copy SMILEScopy InChI
Affinity DataIC50: 2.80E+3nMAssay Description:Inhibition of class A beta-lactamase derived from Staphylococcus aureus strain PC1More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2HQ3Z41PubMed
TargetBeta-lactamase(Enterobacter cloacae)
Southern Methodist University

Curated by ChEMBL
LigandPNGBDBM50157692(CHEMBL1439 | CL-307579 | Sodium; (2S,3S,5R)-3-meth...)copy SMILEScopy InChI
Affinity DataIC50: 320nMAssay Description:Inhibition of class A TEM-1 beta-lactamase derived from Enterobacter cloacaeMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2HQ3Z41PubMed
TargetBeta-lactamase(Enterobacter cloacae)
Southern Methodist University

Curated by ChEMBL
LigandPNGBDBM50157692(CHEMBL1439 | CL-307579 | Sodium; (2S,3S,5R)-3-meth...)copy SMILEScopy InChI
Affinity DataIC50: 4.98E+4nMAssay Description:The compound was evaluated for inhibition against Class C beta-lactamase derived from Enterobacter cloacae P99More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2HQ3Z41PubMed
TargetBeta-lactamase TEM(Escherichia coli)
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50157692(CHEMBL1439 | CL-307579 | Sodium; (2S,3S,5R)-3-meth...)copy SMILEScopy InChI
Affinity DataIC50: 122nMAssay Description:Beta-Lactamase inhibitory activity against representative class A (TEM-1) serine enzymeMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q22Z14ZGPubMed
TargetBeta-lactamase TEM(Escherichia coli)
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50157692(CHEMBL1439 | CL-307579 | Sodium; (2S,3S,5R)-3-meth...)copy SMILEScopy InChI
Affinity DataIC50: 100nMAssay Description:Inhibition of Escherichia coli TEM1More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2542N22PubMed
TargetBeta-lactamase(Enterobacter cloacae)
Southern Methodist University

Curated by ChEMBL
LigandPNGBDBM50157692(CHEMBL1439 | CL-307579 | Sodium; (2S,3S,5R)-3-meth...)copy SMILEScopy InChI
Affinity DataIC50: 8.40E+4nMAssay Description:Inhibition of Enterobacter cloacae AmpCMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2542N22PubMed
TargetMetallo-beta-lactamase type 2(Bacteroides fragilis)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50157692(CHEMBL1439 | CL-307579 | Sodium; (2S,3S,5R)-3-meth...)copy SMILEScopy InChI
Affinity DataIC50: 4.00E+5nMAssay Description:Inhibition of Bacteroides fragilis CcrAMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2542N22PubMed
TargetBeta-lactamase(Staphylococcus aureus)
Southern Methodist University

Curated by ChEMBL
LigandPNGBDBM50157692(CHEMBL1439 | CL-307579 | Sodium; (2S,3S,5R)-3-meth...)copy SMILEScopy InChI
Affinity DataIC50: 2.57E+3nMAssay Description:The compound was evaluated for inhibition against Beta-lactamase derived from Staphylococcus aureusMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2NG4PVBPubMed
TargetBeta-lactamase(Escherichia coli)
MEIJI SEIKA PHARMA CO., LTD.

US Patent
LigandPNGBDBM50157692(CHEMBL1439 | CL-307579 | Sodium; (2S,3S,5R)-3-meth...)copy SMILEScopy InChI
Affinity DataIC50: 4.77E+4nMAssay Description:Inhibitory activity of the compound against AmpC (class C) beta-lactamaseMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2TB163QPubMed