null

SMILES Clc1cccc(COC(=O)Nc2ccc3CC4CCC(Cc3c2)C4NS(=O)(=O)c2ccccc2)c1

InChI Key InChIKey=AMBNQJOUORUGOZ-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50157970   

TargetGamma-secretase subunit APH-1A/Gamma-secretase subunit APH-1B/Gamma-secretase subunit PEN-2/Nicastrin/Presenilin-1/Presenilin-2(Homo sapiens (Human))
Merck Sharp & Dohme Research Laboratories

Curated by ChEMBL

LigandBDBM50157970((13-Benzenesulfonylamino-tricyclo[8.2.1.0*3,8*]tri...)copy SMILEScopy InChI

Affinity DataIC50: 412nMAssay Description:Inhibitory concentration against Gamma-secretase in whole cell inhibition assay using SH-SY5Y cellsMore data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
B.MOADantibodypediaantibodypediaantibodypediaantibodypediaantibodypediaantibodypediaGoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2445KZQPubMed