null
SMILES COc1cc(CC=C)ccc1O
InChI Key InChIKey=RRAFCDWBNXTKKO-UHFFFAOYSA-N
PDB links: 4 PDB IDs match this monomer.
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 14 hits for monomerid = 50164168
Affinity DataIC50: 3.41E+4nMpH: 9.0 T: 2°CAssay Description:Lipoxygenase activity was measured in borate buffer solutions (0.1 M, pH 9) using the method described in the literature [Malterud et al., J. Agric. ...More data for this Ligand-Target Pair
TargetSecreted chorismate mutase(Mycobacterium tuberculosis H37Rv)
Birla Institute of Technology & Science-Pilani
Birla Institute of Technology & Science-Pilani
Affinity DataIC50: 2.86E+4nMpH: 7.5 T: 2°CAssay Description:Reaction volumes of 0.4 mL of chorismate (typically, 1 mM) in 50 mM Tris-HCl (pH 7.5), 0.5 mM EDTA, 0.1 mg/mL bovine serum albumin, and 10 mM β-...More data for this Ligand-Target Pair
Affinity DataIC50: 1.29E+5nMAssay Description:Inhibition of COX2 by scintillation proximity assayMore data for this Ligand-Target Pair
Affinity DataIC50: 1.90E+4nMAssay Description:Antagonist activity at AR in human MDA-kb2 cells cotransfected with MMTV-luc assessed as decrease in DHT-induced luciferase activity by reporter gene...More data for this Ligand-Target Pair
Affinity DataIC50: 1.29E+5nMAssay Description:Inhibition of COX2More data for this Ligand-Target Pair
Affinity DataIC50: 1.10E+4nMAssay Description:Inhibition of COX1More data for this Ligand-Target Pair
In DepthDetails
TargetTransient receptor potential cation channel subfamily A member 1(Homo sapiens (Human))
University of Hull
Curated by ChEMBL
University of Hull
Curated by ChEMBL
Affinity DataEC50: 1.70E+5nMAssay Description:Agonist activity at human TRPA1 expressed in HEK293 cells assessed as increase in calcium influx by Fluo-4-AM dye based fluorescence assayMore data for this Ligand-Target Pair
TargetTransient receptor potential cation channel subfamily A member 1(Homo sapiens (Human))
University of Hull
Curated by ChEMBL
University of Hull
Curated by ChEMBL
Affinity DataEC50: 1.68E+5nMAssay Description:Agonist activity at human TRPA1 expressed in HEK293 cells assessed as increase in calcium influx by Fluo-4-AM dye based fluorescence assayMore data for this Ligand-Target Pair
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
School of Advanced Sciences
Curated by ChEMBL
School of Advanced Sciences
Curated by ChEMBL
Affinity DataIC50: 2.60E+4nMAssay Description:Inhibition of human PMNL 5-LOX using arachidonic acid as substrate after 5 mins by HPLC methodMore data for this Ligand-Target Pair
Affinity DataIC50: 3.75E+6nMAssay Description:Inhibition of beta-glucuronidase (unknown origin)More data for this Ligand-Target Pair
TargetTransient receptor potential cation channel subfamily A member 1(Homo sapiens (Human))
University of Hull
Curated by ChEMBL
University of Hull
Curated by ChEMBL
Affinity DataEC50: 1.16E+5nMAssay Description:Agonist activity at TRPA1 (unknown origin) by calcium imaging assayMore data for this Ligand-Target Pair
Affinity DataIC50: 9.23E+5nMAssay Description:Inhibition of mushroom tyrosinase using L-tyrosine as substrate measured after 15 mins by microplate reader analysisMore data for this Ligand-Target Pair
TargetTransient receptor potential cation channel subfamily A member 1(Homo sapiens (Human))
University of Hull
Curated by ChEMBL
University of Hull
Curated by ChEMBL
Affinity DataEC50: 2.61E+5nMAssay Description:Agonist activity at human TRPA1 expressed in HEK293 assessed as increase in calcium influx by two electrode voltage clamp methodMore data for this Ligand-Target Pair