null
SMILES [O-]C(=O)Cc1ccccc1Nc1c(Cl)cccc1Cl
InChI Key InChIKey=DCOPUUMXTXDBNB-UHFFFAOYSA-M
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 36 hits for monomerid = 50174201
TargetProstaglandin G/H synthase 1(Homo sapiens (Human))
Merck Frosst Centre for Therapeutic Research
Curated by PDSP Ki Database
Merck Frosst Centre for Therapeutic Research
Curated by PDSP Ki Database
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Dallas Department of Veterans Affairs Medical Center
Curated by PDSP Ki Database
Dallas Department of Veterans Affairs Medical Center
Curated by PDSP Ki Database
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Dallas Department of Veterans Affairs Medical Center
Curated by PDSP Ki Database
Dallas Department of Veterans Affairs Medical Center
Curated by PDSP Ki Database
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Dallas Department of Veterans Affairs Medical Center
Curated by PDSP Ki Database
Dallas Department of Veterans Affairs Medical Center
Curated by PDSP Ki Database
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Dallas Department of Veterans Affairs Medical Center
Curated by PDSP Ki Database
Dallas Department of Veterans Affairs Medical Center
Curated by PDSP Ki Database
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Dallas Department of Veterans Affairs Medical Center
Curated by PDSP Ki Database
Dallas Department of Veterans Affairs Medical Center
Curated by PDSP Ki Database
TargetProstaglandin G/H synthase 1(Homo sapiens (Human))
Merck Frosst Centre for Therapeutic Research
Curated by PDSP Ki Database
Merck Frosst Centre for Therapeutic Research
Curated by PDSP Ki Database
TargetProstaglandin G/H synthase 1(Homo sapiens (Human))
Merck Frosst Centre for Therapeutic Research
Curated by PDSP Ki Database
Merck Frosst Centre for Therapeutic Research
Curated by PDSP Ki Database
TargetProstaglandin G/H synthase 1(Homo sapiens (Human))
Merck Frosst Centre for Therapeutic Research
Curated by PDSP Ki Database
Merck Frosst Centre for Therapeutic Research
Curated by PDSP Ki Database
TargetProstaglandin G/H synthase 1(Homo sapiens (Human))
Merck Frosst Centre for Therapeutic Research
Curated by PDSP Ki Database
Merck Frosst Centre for Therapeutic Research
Curated by PDSP Ki Database
Affinity DataKi: 3.00E+5nMAssay Description:Competitive inhibition of Capra hircus (goat) brain DPP-3 using Arg-Arg-4mbetaNA as substrate assessed as liberation of 4mbetaNA from substrate prein...More data for this Ligand-Target Pair
Affinity DataKi: 8.05E+5nM ΔG°: -4.22kcal/mole IC50: 1.64E+6nMpH: 10.5 T: 2°CAssay Description:The enzyme assay was based on the estimation of p-nitrophenol at 412nm. The molar extinction coefficient of p-nitrophenol was used to calculate enzy...More data for this Ligand-Target Pair
Affinity DataIC50: 4.20E+3nMAssay Description:Inhibition of ovine COX2-mediated prostaglandin alpha production by enzyme immuno assayMore data for this Ligand-Target Pair
Affinity DataIC50: 2.20E+5nMAssay Description:Inhibition of Capra hircus (goat) brain DPP-3 using Arg-Arg-4mbetaNA as substrate assessed as liberation of 4mbetaNA from substrateMore data for this Ligand-Target Pair
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Dallas Department of Veterans Affairs Medical Center
Curated by PDSP Ki Database
Dallas Department of Veterans Affairs Medical Center
Curated by PDSP Ki Database
Affinity DataIC50: 800nMAssay Description:Inhibition of human recombinant COX2 catalytic activity using arachidonic acid as substrate pre-incubated for 10 mins followed by substrate addition ...More data for this Ligand-Target Pair
Affinity DataIC50: 3.90E+3nMAssay Description:Inhibition of ovine COX1 catalytic activity using arachidonic acid as substrate pre-incubated for 10 mins followed by substrate addition and measured...More data for this Ligand-Target Pair
Affinity DataIC50: 3.80E+3nMAssay Description:Inhibition of ovine COX1 using arachidonic acid as substrate preincubated for 10 mins followed by substrate addition and measured after 2 mins by EIAMore data for this Ligand-Target Pair
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Dallas Department of Veterans Affairs Medical Center
Curated by PDSP Ki Database
Dallas Department of Veterans Affairs Medical Center
Curated by PDSP Ki Database
Affinity DataIC50: 840nMAssay Description:Inhibition of human recombinant COX2 using arachidonic acid as substrate preincubated for 10 mins followed by substrate addition and measured after 2...More data for this Ligand-Target Pair
Affinity DataIC50: 3.90E+3nMAssay Description:Inhibition of ovine COX1 by colorimetric analysisMore data for this Ligand-Target Pair
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Dallas Department of Veterans Affairs Medical Center
Curated by PDSP Ki Database
Dallas Department of Veterans Affairs Medical Center
Curated by PDSP Ki Database
Affinity DataIC50: 800nMAssay Description:Inhibition of human recombinant COX2 by colorimetric analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 3.80E+3nMAssay Description:Inhibition of ovine COX-1 using arachidonic acid as substrate preincubated with enzyme for 5 mins followed by substrate addition by colorimetric anal...More data for this Ligand-Target Pair
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Dallas Department of Veterans Affairs Medical Center
Curated by PDSP Ki Database
Dallas Department of Veterans Affairs Medical Center
Curated by PDSP Ki Database
Affinity DataIC50: 840nMAssay Description:Inhibition of human recombinant COX-2 using arachidonic acid as substrate preincubated with enzyme for 5 mins followed by substrate addition by color...More data for this Ligand-Target Pair
Affinity DataIC50: 3.63E+5nMAssay Description:CLC-2 activity using cell-free assays, e.g., binding assays; with purified enzymes.More data for this Ligand-Target Pair
Affinity DataIC50: 250nMAssay Description:Inhibition of ovine COX1-mediated prostaglandin alpha production by enzyme immuno assayMore data for this Ligand-Target Pair
TargetProstaglandin G/H synthase 1(Homo sapiens (Human))
Merck Frosst Centre for Therapeutic Research
Curated by PDSP Ki Database
Merck Frosst Centre for Therapeutic Research
Curated by PDSP Ki Database
Affinity DataIC50: 3nMAssay Description:Inhibition of COX-1 (unknown origin)More data for this Ligand-Target Pair
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Dallas Department of Veterans Affairs Medical Center
Curated by PDSP Ki Database
Dallas Department of Veterans Affairs Medical Center
Curated by PDSP Ki Database
Affinity DataIC50: 840nMAssay Description:Inhibition of human recombinant COX-2 by EIA methodMore data for this Ligand-Target Pair
Affinity DataIC50: 3.80E+3nMAssay Description:Inhibition of ovine COX-1 by EIA methodMore data for this Ligand-Target Pair
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Dallas Department of Veterans Affairs Medical Center
Curated by PDSP Ki Database
Dallas Department of Veterans Affairs Medical Center
Curated by PDSP Ki Database
Affinity DataIC50: 800nMAssay Description:Inhibition of recombinant human COX2 assessed as reduction in PGF2alpha production using arachidonic acid as substrate by colorimetric methodMore data for this Ligand-Target Pair
In DepthDetails
Affinity DataIC50: 1.00E+9nMAssay Description:In vitro inhibition of bovine prostaglandin G/H synthase, using bovine seminal vesicle microsomal preparations; IC50 in umol/LMore data for this Ligand-Target Pair
Affinity DataIC50: 3.10E+3nMAssay Description:Inhibition of ovine COX2 by enzyme immuno assayMore data for this Ligand-Target Pair
Affinity DataIC50: 220nMAssay Description:Inhibition of ovine COX1 by enzyme immuno assayMore data for this Ligand-Target Pair
TargetAldo-keto reductase family 1 member C3(Homo sapiens (Human))
University of Ljubljana
Curated by ChEMBL
University of Ljubljana
Curated by ChEMBL
Affinity DataIC50: 2.60E+3nMAssay Description:Inhibition of recombinant human AKR1C3More data for this Ligand-Target Pair
Affinity DataIC50: 160nMAssay Description:Inhibition of ovine COX1 assessed as PGF2alpha production from PGH2 after 5 mins by enzyme immunoassayMore data for this Ligand-Target Pair
Affinity DataIC50: 2.50E+3nMAssay Description:Inhibition of ovine COX2 assessed as PGF2alpha production from PGH2 after 5 mins by enzyme immunoassayMore data for this Ligand-Target Pair
Affinity DataIC50: 3.90E+3nMAssay Description:Inhibition of ovine COX1 assessed as reduction in PGF2alpha production using arachidonic acid as substrate by colorimetric methodMore data for this Ligand-Target Pair