null
SMILES CC1(C)[C@H](CC[C@@]2(C)[C@H]1CC[C@]1(C)[C@@H]2C(=O)C=C2[C@@H]3C[C@](C)(CC[C@]3(C)CC[C@@]12C)C(O)=O)O[C@H]1O[C@@H]([C@@H](O)[C@H](O)[C@H]1O[C@@H]1O[C@@H]([C@@H](O)[C@H](O)[C@H]1O)C(O)=O)C(O)=O
InChI Key InChIKey=LPLVUJXQOOQHMX-QWBHMCJMSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 20 hits for monomerid = 50185127
TargetATP-binding cassette sub-family C member 2(Rattus norvegicus)
University of Tokyo
Curated by ChEMBL
University of Tokyo
Curated by ChEMBL
Affinity DataKi: 840nMAssay Description:TP_TRANSPORTER: inhibition of DNP-SG uptake in bile canalicular membrane vesicles from SD ratMore data for this Ligand-Target Pair
TargetATP-binding cassette sub-family C member 2(Rattus norvegicus)
University of Tokyo
Curated by ChEMBL
University of Tokyo
Curated by ChEMBL
Affinity DataKi: 1.91E+3nMAssay Description:TP_TRANSPORTER: inhibition of SN-38 uptake in bile canalicular membrane vesicles from SD ratMore data for this Ligand-Target Pair
TargetSolute carrier organic anion transporter family member 1B2(Rattus norvegicus)
University of Zurich
Curated by ChEMBL
University of Zurich
Curated by ChEMBL
Affinity DataKi: 6.10E+3nMAssay Description:TP_TRANSPORTER: inhibition of E1S uptake in Xenopus laevis oocytesMore data for this Ligand-Target Pair
TargetSolute carrier organic anion transporter family member 1B3(Homo sapiens (Human))
University of Zurich
Curated by ChEMBL
University of Zurich
Curated by ChEMBL
Affinity DataKi: 1.25E+4nMAssay Description:TP_TRANSPORTER: inhibition of BSP uptake in Xenopus laevis oocytesMore data for this Ligand-Target Pair
TargetSolute carrier organic anion transporter family member 1B1(Homo sapiens (Human))
University of Zurich
Curated by ChEMBL
University of Zurich
Curated by ChEMBL
Affinity DataKi: 1.59E+4nMAssay Description:TP_TRANSPORTER: inhibition of E1S uptake in Xenopus laevis oocytesMore data for this Ligand-Target Pair
Target11-beta-hydroxysteroid dehydrogenase 1(Mus musculus (mouse))
Chinese Academy of Sciences
Curated by ChEMBL
Chinese Academy of Sciences
Curated by ChEMBL
Affinity DataIC50: 15nMAssay Description:Inhibition of mouse liver microsome 11betaHSD1 expressed in HEK293 cells assessed as conversion of [3H]cortisone into [3H]cortisol by scintillation p...More data for this Ligand-Target Pair
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Chinese Academy of Sciences
Curated by ChEMBL
Chinese Academy of Sciences
Curated by ChEMBL
Affinity DataIC50: 10nMAssay Description:Inhibition of human microsomal 11beta-HSD1 expressed in HEK293 cells assessed as conversion of [3H]cortisone to [3H]cortisol by scintillation proximi...More data for this Ligand-Target Pair
Target11-beta-hydroxysteroid dehydrogenase 1(Mus musculus (mouse))
Chinese Academy of Sciences
Curated by ChEMBL
Chinese Academy of Sciences
Curated by ChEMBL
Affinity DataIC50: 8nMAssay Description:Inhibition of mouse microsomal 11beta-HSD1 expressed in HEK293 cells assessed as conversion of [3H]cortisone to [3H]cortisol by scintillation proximi...More data for this Ligand-Target Pair
Target11-beta-hydroxysteroid dehydrogenase type 2(Homo sapiens (Human))
Chinese Academy of Sciences
Curated by ChEMBL
Chinese Academy of Sciences
Curated by ChEMBL
Affinity DataIC50: 1nMAssay Description:Inhibition of human microsomal 11beta-HSD2 expressed in HEK293 cells assessed as conversion of [3H]cortisone to [3H]cortisol by scintillation proximi...More data for this Ligand-Target Pair
TargetPancreatic alpha-amylase(Sus scrofa (Pig))
School of Life Science and Biotechnology, Dalian University of Technology, Dalian 116024, Liaoning, China.
Curated by ChEMBL
School of Life Science and Biotechnology, Dalian University of Technology, Dalian 116024, Liaoning, China.
Curated by ChEMBL
Affinity DataIC50: 2.00E+5nMAssay Description:Inhibition of porcine pancreatic alpha-amylase using starch as substrate preincubated for 15 mins followed by substrate addition measured after 10 mi...More data for this Ligand-Target Pair
TargetHigh mobility group protein B1(Homo sapiens (Human))
The Feinstein Institute for Medical Research
Curated by ChEMBL
The Feinstein Institute for Medical Research
Curated by ChEMBL
Affinity DataKd: 1.03E+5nMAssay Description:Binding affinity to recombinant HMGB1 A box region (1 to 89 residues) (unknown origin) expressed Escherichia coli after 5 mins by fluorescence-based ...More data for this Ligand-Target Pair
TargetHigh mobility group protein B1(Homo sapiens (Human))
The Feinstein Institute for Medical Research
Curated by ChEMBL
The Feinstein Institute for Medical Research
Curated by ChEMBL
Affinity DataKd: 8.70E+4nMAssay Description:Binding affinity to recombinant HMGB1 B box region (90 to 175 residues) (unknown origin) expressed Escherichia coli after 5 mins by fluorescence-base...More data for this Ligand-Target Pair
TargetBeta-glucuronidase(Escherichia coli (Enterobacteria))
University of KwaZulu-Natal
Curated by ChEMBL
University of KwaZulu-Natal
Curated by ChEMBL
Affinity DataIC50: 1.22E+4nMAssay Description:Inhibition of Escherichia coli beta-glucuronidaseMore data for this Ligand-Target Pair
Affinity DataIC50: 9.72E+4nMAssay Description:Inhibition of rat liver beta-glucuronidaseMore data for this Ligand-Target Pair
TargetHigh mobility group protein B1(Homo sapiens (Human))
The Feinstein Institute for Medical Research
Curated by ChEMBL
The Feinstein Institute for Medical Research
Curated by ChEMBL
Affinity DataKd: 1.50E+5nMAssay Description:Binding affinity to HMGB1 (unknown origin)More data for this Ligand-Target Pair
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Chinese Academy of Sciences
Curated by ChEMBL
Chinese Academy of Sciences
Curated by ChEMBL
Affinity DataEC50: 10nMAssay Description:Inhibition of human 11beta-HSD1 expressed in HEK293 cells assessed as [3H]cortisol production after 60 mins by SPAMore data for this Ligand-Target Pair
Target11-beta-hydroxysteroid dehydrogenase type 2(Homo sapiens (Human))
Chinese Academy of Sciences
Curated by ChEMBL
Chinese Academy of Sciences
Curated by ChEMBL
Affinity DataEC50: 1nMAssay Description:Inhibition of human 11beta-HSD2 expressed in HEK293 cells assessed as [3H]cortisol production after 60 mins by SPAMore data for this Ligand-Target Pair
TargetHigh mobility group protein B1(Homo sapiens (Human))
The Feinstein Institute for Medical Research
Curated by ChEMBL
The Feinstein Institute for Medical Research
Curated by ChEMBL
Affinity DataKd: 1.50E+5nMAssay Description:Binding affinity to full-length N-terminal 6His-tagged HMGB1 (unknown origin) by NMR spectraMore data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Korea Research Institute of Bioscience and Biotechnology
Curated by ChEMBL
Korea Research Institute of Bioscience and Biotechnology
Curated by ChEMBL
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human recombinant PTP1BMore data for this Ligand-Target Pair
Target11-beta-hydroxysteroid dehydrogenase 1(Mus musculus (mouse))
Chinese Academy of Sciences
Curated by ChEMBL
Chinese Academy of Sciences
Curated by ChEMBL
Affinity DataEC50: 8nMAssay Description:Inhibition of mouse 11beta-HSD1 expressed in HEK293 cells assessed as [3H]cortisol production after 60 mins by SPAMore data for this Ligand-Target Pair