null

SMILES Fc1ccc(F)c(c1)[C@@]1(CCC[C@H](C1)C=O)S(=O)(=O)c1ccc(Cl)cc1

InChI Key InChIKey=MRNWWQISTSVGSE-YJYMSZOUSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50186576   

TargetGamma-secretase subunit APH-1A/Gamma-secretase subunit APH-1B/Gamma-secretase subunit PEN-2/Nicastrin/Presenilin-1/Presenilin-2(Homo sapiens (Human))
Merck Sharp and Dohme Research Laboratories

Curated by ChEMBL

LigandBDBM50186576(CHEMBL379758 | cis-3-(4-chlorophenylsulfonyl)-3-(2...)copy SMILEScopy InChI

Affinity DataIC50: 77nMAssay Description:Inhibition of gamma secretase expressed in SH-SY5Y cellsMore data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
B.MOADantibodypediaantibodypediaantibodypediaantibodypediaantibodypediaantibodypediaGoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2BP02DTPubMed