null
SMILES CC(=O)Nc1cccc(c1)N1CCN(CCCCNS(=O)(=O)c2ccc(C)cc2)CC1
InChI Key InChIKey=GDSVOHILVQPEJQ-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 5 hits for monomerid = 50187387
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Predix Pharmaceuticals Ltd.
Curated by ChEMBL
Predix Pharmaceuticals Ltd.
Curated by ChEMBL
Affinity DataKi: 6.80nMAssay Description:Displacement of [3H]8-OH-DPAT from human 5HT1A receptor in HEK293 cellsMore data for this Ligand-Target Pair
TargetAlpha-1A/Alpha-1B/Alpha-1D adrenergic receptor(Rattus norvegicus (rat))
Predix Pharmaceuticals Ltd.
Curated by ChEMBL
Predix Pharmaceuticals Ltd.
Curated by ChEMBL
Affinity DataKi: >3.50E+3nMAssay Description:Displacement of [3H]prazosin from adrenergic alpha-1 receptor in rat cerebral cortex cellsMore data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Predix Pharmaceuticals Ltd.
Curated by ChEMBL
Predix Pharmaceuticals Ltd.
Curated by ChEMBL
Affinity DataIC50: 300nMAssay Description:Inhibition of hERG potassium channel in HEK293 cells by patch clamp assayMore data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Predix Pharmaceuticals Ltd.
Curated by ChEMBL
Predix Pharmaceuticals Ltd.
Curated by ChEMBL
Affinity DataIC50: 300nMAssay Description:Inhibition of human ERG channelMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Predix Pharmaceuticals Ltd.
Curated by ChEMBL
Predix Pharmaceuticals Ltd.
Curated by ChEMBL
Affinity DataEC50: 20nMAssay Description:Activity against 5HT1A receptor by Gi-[35S]GTPgammaS binding assayMore data for this Ligand-Target Pair