null

SMILES O=C(N[C@@H](Cc1ccc(cc1)-c1ccc(cc1)C#N)C#N)[C@@H]1CNCCCO1

InChI Key InChIKey=FCRODBUNBQJNPU-SFTDATJTSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 12 hits for monomerid = 50195236   

TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
CHARLES RIVER DISCOVERY RESEARCH SERVICES UK LIMITED

Curated by ChEMBL
LigandPNGBDBM50195236(CHEMBL3927609 | US10287258, Example 1 | US10669245...)copy SMILEScopy InChI
Affinity DataIC50: 1.70E+4nMAssay Description:Inhibition of human ERGMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2Z321K4PubMed
TargetDipeptidyl peptidase 1(Homo sapiens (Human))
CHARLES RIVER DISCOVERY RESEARCH SERVICES UK LIMITED

Curated by ChEMBL
LigandPNGBDBM50195236(CHEMBL3927609 | US10287258, Example 1 | US10669245...)copy SMILEScopy InChI
Affinity DataIC50: 32nMAssay Description:Inhibition of DPP1 in human U937 cells using Gly-Phe-AFC as substrate preincubated for 60 mins followed by substrate addition by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2Z321K4PubMed
TargetDipeptidyl peptidase 1(Homo sapiens (Human))
CHARLES RIVER DISCOVERY RESEARCH SERVICES UK LIMITED

Curated by ChEMBL
LigandPNGBDBM50195236(CHEMBL3927609 | US10287258, Example 1 | US10669245...)copy SMILEScopy InChI
Affinity DataIC50: 40nMAssay Description:Inhibition of human recombinant DPP1 using Gly-Arg-AMC as substrate preincubated for 30 mins followed by substrate addition by fluorometric assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2Z321K4PubMed
TargetDipeptidyl peptidase 1(Homo sapiens (Human))
CHARLES RIVER DISCOVERY RESEARCH SERVICES UK LIMITED

Curated by ChEMBL
LigandPNGBDBM50195236(CHEMBL3927609 | US10287258, Example 1 | US10669245...)copy SMILEScopy InChI
Affinity DataIC50: 35.5nMMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2F76HN2
TargetDipeptidyl peptidase 1(Homo sapiens (Human))
CHARLES RIVER DISCOVERY RESEARCH SERVICES UK LIMITED

Curated by ChEMBL
LigandPNGBDBM50195236(CHEMBL3927609 | US10287258, Example 1 | US10669245...)copy SMILEScopy InChI
Affinity DataIC50: 35.5nMMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2FB56W4
TargetDipeptidyl peptidase 1(Homo sapiens (Human))
CHARLES RIVER DISCOVERY RESEARCH SERVICES UK LIMITED

Curated by ChEMBL
LigandPNGBDBM50195236(CHEMBL3927609 | US10287258, Example 1 | US10669245...)copy SMILEScopy InChI
Affinity DataIC50: 35.5nMMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2ZG6X5T
TargetDipeptidyl peptidase 1(Homo sapiens (Human))
CHARLES RIVER DISCOVERY RESEARCH SERVICES UK LIMITED

Curated by ChEMBL
LigandPNGBDBM50195236(CHEMBL3927609 | US10287258, Example 1 | US10669245...)copy SMILEScopy InChI
Affinity DataIC50: 35.5nMAssay Description:The activity of DPP1 was determined by measuring the enzymatic release of aminomethyl coumarin (AMC) from the peptide substrate (H-Gly-Arg-AMC), whic...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2RJ4MTPUS Patent
TargetDipeptidyl peptidase 1(Homo sapiens (Human))
CHARLES RIVER DISCOVERY RESEARCH SERVICES UK LIMITED

Curated by ChEMBL
LigandPNGBDBM50195236(CHEMBL3927609 | US10287258, Example 1 | US10669245...)copy SMILEScopy InChI
Affinity DataIC50: 35.5nMAssay Description:The activity of DPP1 was determined by measuring the enzymatic release of aminomethyl coumarin (AMC) from the peptide substrate (H-Gly-Arg-AMC), whic...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2862KG7US Patent
TargetDipeptidyl peptidase 1(Homo sapiens (Human))
CHARLES RIVER DISCOVERY RESEARCH SERVICES UK LIMITED

Curated by ChEMBL
LigandPNGBDBM50195236(CHEMBL3927609 | US10287258, Example 1 | US10669245...)copy SMILEScopy InChI
Affinity DataIC50: 35.5nMAssay Description:Examples 1-35: The activity of DPP1 was determined by measuring the enzymatic release of aminomethyl coumarin (AMC) from the peptide substrate (H-Gly...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2Q243DZUS Patent
TargetDipeptidyl peptidase 1(Homo sapiens (Human))
CHARLES RIVER DISCOVERY RESEARCH SERVICES UK LIMITED

Curated by ChEMBL
LigandPNGBDBM50195236(CHEMBL3927609 | US10287258, Example 1 | US10669245...)copy SMILEScopy InChI
Affinity DataIC50: 35.5nMMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q24X5CXQ
TargetDipeptidyl peptidase 1(Homo sapiens (Human))
CHARLES RIVER DISCOVERY RESEARCH SERVICES UK LIMITED

Curated by ChEMBL
LigandPNGBDBM50195236(CHEMBL3927609 | US10287258, Example 1 | US10669245...)copy SMILEScopy InChI
Affinity DataIC50: 35.5nMMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2H99949
TargetDipeptidyl peptidase 1(Homo sapiens (Human))
CHARLES RIVER DISCOVERY RESEARCH SERVICES UK LIMITED

Curated by ChEMBL
LigandPNGBDBM50195236(CHEMBL3927609 | US10287258, Example 1 | US10669245...)copy SMILEScopy InChI
Affinity DataIC50: 60.3nMMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2FB56W4