null

SMILES COC[C@@H]1CCCN1S(=O)(=O)c1ccc2N(C)C(=O)C(=O)c2c1

InChI Key InChIKey=SMINLRKVPPXJGK-JTQLQIEISA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 10 hits for monomerid = 50200302   

TargetCaspase-3(Homo sapiens (Human))
University Hospital of the Westfälische Wilhelms-Universität

Curated by ChEMBL
LigandPNGBDBM50200302((S)-5-(2-(methoxymethyl)pyrrolidin-1-ylsulfonyl)-1...)copy SMILEScopy InChI
Affinity DataKi:  1.20nMAssay Description:Binding affinity to human caspase 3More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2513XV1PubMed
TargetCaspase-7(Homo sapiens (Human))
Westf£lische Wilhelms-Universit£t M£nster

Curated by ChEMBL
LigandPNGBDBM50200302((S)-5-(2-(methoxymethyl)pyrrolidin-1-ylsulfonyl)-1...)copy SMILEScopy InChI
Affinity DataIC50: 304nMAssay Description:Inhibition of human recombinant caspase 7 using Ac-DEVD-AMC substrate assessed as accumulation of cleaved fluorogenic productMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2474CGMPubMed
TargetCaspase-8(Homo sapiens (Human))
University Hospital of the Westfälische Wilhelms-Universität

Curated by ChEMBL
LigandPNGBDBM50200302((S)-5-(2-(methoxymethyl)pyrrolidin-1-ylsulfonyl)-1...)copy SMILEScopy InChI
Affinity DataIC50: 5.00E+5nMAssay Description:Inhibition of caspase 8More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2513XV1PubMed
TargetCaspase-7(Homo sapiens (Human))
Westf£lische Wilhelms-Universit£t M£nster

Curated by ChEMBL
LigandPNGBDBM50200302((S)-5-(2-(methoxymethyl)pyrrolidin-1-ylsulfonyl)-1...)copy SMILEScopy InChI
Affinity DataIC50: 304nMAssay Description:Inhibition of human recombinant caspase 7More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25Q4W0PPubMed
TargetCaspase-1(Homo sapiens (Human))
University Hospital of the Westfälische Wilhelms-Universität

Curated by ChEMBL
LigandPNGBDBM50200302((S)-5-(2-(methoxymethyl)pyrrolidin-1-ylsulfonyl)-1...)copy SMILEScopy InChI
Affinity DataIC50: 2.50E+4nMAssay Description:Inhibition of caspase 1More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2513XV1PubMed
TargetCaspase-3(Homo sapiens (Human))
University Hospital of the Westfälische Wilhelms-Universität

Curated by ChEMBL
LigandPNGBDBM50200302((S)-5-(2-(methoxymethyl)pyrrolidin-1-ylsulfonyl)-1...)copy SMILEScopy InChI
Affinity DataIC50: 2.40nMAssay Description:Inhibition of caspase 3More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2513XV1PubMed
TargetCaspase-6(Homo sapiens (Human))
University Hospital of the Westfälische Wilhelms-Universität

Curated by ChEMBL
LigandPNGBDBM50200302((S)-5-(2-(methoxymethyl)pyrrolidin-1-ylsulfonyl)-1...)copy SMILEScopy InChI
Affinity DataIC50: 5.00E+5nMAssay Description:Inhibition of caspase 6More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2513XV1PubMed
TargetCaspase-3(Homo sapiens (Human))
University Hospital of the Westfälische Wilhelms-Universität

Curated by ChEMBL
LigandPNGBDBM50200302((S)-5-(2-(methoxymethyl)pyrrolidin-1-ylsulfonyl)-1...)copy SMILEScopy InChI
Affinity DataIC50: 2.40nMAssay Description:Inhibition of human recombinant caspase 3More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25Q4W0PPubMed
TargetCaspase-3(Homo sapiens (Human))
University Hospital of the Westfälische Wilhelms-Universität

Curated by ChEMBL
LigandPNGBDBM50200302((S)-5-(2-(methoxymethyl)pyrrolidin-1-ylsulfonyl)-1...)copy SMILEScopy InChI
Affinity DataIC50: 2.40nMAssay Description:Inhibition of human recombinant caspase 3 using Ac-DEVD-AMC substrate assessed as accumulation of cleaved fluorogenic productMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2474CGMPubMed
TargetCaspase-7(Homo sapiens (Human))
Westf£lische Wilhelms-Universit£t M£nster

Curated by ChEMBL
LigandPNGBDBM50200302((S)-5-(2-(methoxymethyl)pyrrolidin-1-ylsulfonyl)-1...)copy SMILEScopy InChI
Affinity DataIC50: 304nMAssay Description:Inhibition of caspase 7More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2513XV1PubMed