null

SMILES O=C\C=C\c1ccccc1

InChI Key InChIKey=KJPRLNWUNMBNBZ-QPJJXVBHSA-N

PDB links: 2 PDB IDs match this monomer.

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 14 hits for monomerid = 50203065   

TargetTransient receptor potential cation channel subfamily A member 1(Homo sapiens (Human))
Renovis, Inc.

Curated by ChEMBL
LigandPNGBDBM50203065(3-phenylacrylaldehyde | 3-phenylprop-2-enal | CHEM...)copy SMILEScopy InChI
Affinity DataEC50:  5.14E+4nMAssay Description:Agonist activity at human TRPA1 expressed in HEK293 cells assessed as [45]Ca2+ influx by microbeta plate countMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2K074C4PubMed
TargetCell division protein FtsZ(Escherichia coli)
Shandong University

Curated by ChEMBL
LigandPNGBDBM50203065(3-phenylacrylaldehyde | 3-phenylprop-2-enal | CHEM...)copy SMILEScopy InChI
Affinity DataIC50: 6.86E+3nMAssay Description:Inhibition of Escherichia coli FtsZ polymerizationMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2S75J14PubMed
TargetCell division protein FtsZ(Escherichia coli)
Shandong University

Curated by ChEMBL
LigandPNGBDBM50203065(3-phenylacrylaldehyde | 3-phenylprop-2-enal | CHEM...)copy SMILEScopy InChI
Affinity DataIC50: 5.81E+3nMAssay Description:Inhibition of Escherichia coli FtsZ GTPase activityMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2S75J14PubMed
TargetPolyphenol oxidase 2(Agaricus bisporus (Common mushroom))
Chungnam National University

Curated by ChEMBL
LigandPNGBDBM50203065(3-phenylacrylaldehyde | 3-phenylprop-2-enal | CHEM...)copy SMILEScopy InChI
Affinity DataIC50: 5.20E+5nMAssay Description:Inhibition of mushroom tyrosinase after 10 mins by spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QF8T0KPubMed
TargetTransient receptor potential cation channel subfamily M member 8(Mus musculus)
University of Shizuoka

Curated by ChEMBL
LigandPNGBDBM50203065(3-phenylacrylaldehyde | 3-phenylprop-2-enal | CHEM...)copy SMILEScopy InChI
Affinity DataIC50: 5.00E+5nMAssay Description:Antagonist at TRPM8 isolated from mouse dorsal root ganglion cells expressed in HEK T-REx cells assessed as inhibition of icilin-induced intracellula...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20P11H1PubMed
TargetTransient receptor potential cation channel subfamily M member 8(Mus musculus)
University of Shizuoka

Curated by ChEMBL
LigandPNGBDBM50203065(3-phenylacrylaldehyde | 3-phenylprop-2-enal | CHEM...)copy SMILEScopy InChI
Affinity DataIC50: 5.00E+5nMAssay Description:Antagonist at TRPM8 isolated from mouse dorsal root ganglion cells expressed in HEK T-REx cells assessed as inhibition of menthol-induced intracellul...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20P11H1PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
School of Advanced Sciences

Curated by ChEMBL
LigandPNGBDBM50203065(3-phenylacrylaldehyde | 3-phenylprop-2-enal | CHEM...)copy SMILEScopy InChI
Affinity DataIC50: 3.50E+4nMAssay Description:Inhibition of human PMNL 5-LOX using arachidonic acid as substrate after 5 mins by HPLC methodMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2251NNQPubMed
TargetTransient receptor potential cation channel subfamily A member 1(Homo sapiens (Human))
Renovis, Inc.

Curated by ChEMBL
LigandPNGBDBM50203065(3-phenylacrylaldehyde | 3-phenylprop-2-enal | CHEM...)copy SMILEScopy InChI
Affinity DataEC50:  1.90E+4nMAssay Description:Activation of TRPA1More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2D21ZHQPubMed
TargetTransient receptor potential cation channel subfamily A member 1(Homo sapiens (Human))
Renovis, Inc.

Curated by ChEMBL
LigandPNGBDBM50203065(3-phenylacrylaldehyde | 3-phenylprop-2-enal | CHEM...)copy SMILEScopy InChI
Affinity DataEC50:  6.50E+3nMAssay Description:Activation of TRPA1 channel expressed in CHO cells assessed as increase in intracellular calcium levelsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2416Z02PubMed
TargetXanthine dehydrogenase/oxidase(Homo sapiens (Human))
National Institute of Medicinal Materials

Curated by ChEMBL
LigandPNGBDBM50203065(3-phenylacrylaldehyde | 3-phenylprop-2-enal | CHEM...)copy SMILEScopy InChI
Affinity DataIC50: 5.90E+4nMAssay Description:Inhibition of xanthine oxidase- mediated uric acid formation after 5 mins by spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2S46VVZPubMed
TargetTransient receptor potential cation channel subfamily A member 1(Homo sapiens (Human))
Renovis, Inc.

Curated by ChEMBL
LigandPNGBDBM50203065(3-phenylacrylaldehyde | 3-phenylprop-2-enal | CHEM...)copy SMILEScopy InChI
Affinity DataEC50:  9.00E+3nMAssay Description:Agonist activity at human TRPA1 expressed in HEK293 cells assessed as increase in calcium influx by Fluo-4-AM dye based fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2F76GWSPubMed
TargetTransient receptor potential cation channel subfamily A member 1(Homo sapiens (Human))
Renovis, Inc.

Curated by ChEMBL
LigandPNGBDBM50203065(3-phenylacrylaldehyde | 3-phenylprop-2-enal | CHEM...)copy SMILEScopy InChI
Affinity DataEC50:  8.51E+3nMAssay Description:Agonist activity at human TRPA1 expressed in HEK293 cells assessed as increase in calcium influx by Fluo-4-AM dye based fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2F76GWSPubMed
TargetTransient receptor potential cation channel subfamily A member 1(Mus musculus)
University of Hull

Curated by ChEMBL
LigandPNGBDBM50203065(3-phenylacrylaldehyde | 3-phenylprop-2-enal | CHEM...)copy SMILEScopy InChI
Affinity DataEC50:  6.10E+4nMAssay Description:Agonist activity at mouse TRPA1 expressed in CHO cells assessed as increase in calcium influx by Fluo-3 based FLIPR analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2F76GWSPubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50203065(3-phenylacrylaldehyde | 3-phenylprop-2-enal | CHEM...)copy SMILEScopy InChI
Affinity DataIC50: 2.45E+5nMAssay Description:Inhibition of COX2More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27S7PN5PubMed