null

SMILES Cc1cn([C@@H]2O[C@H](COP(O)(=O)OP(O)(=O)OP(O)(O)=O)[C@@H](O)[C@H]2O)c(=O)[nH]c1=O

InChI Key InChIKey=RZCIEJXAILMSQK-JXOAFFINSA-N

PDB links: 1 PDB ID matches this monomer.

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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 12 hits for monomerid = 50205415   

TargetThymidine kinase, cytosolic(Rattus norvegicus)
TBA

Curated by ChEMBL
LigandPNGBDBM50205415(({[({[(2R,3S,4R,5R)-3,4-dihydroxy-5-(5-methyl-2,4-...)copy SMILEScopy InChI
Affinity DataKi:  3.70E+3nMAssay Description:Evaluated for the mixed objective Non-competitive inhibition constant Ki against TdR varied rat mitochondrial thymidine kinaseMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2BZ66M6PubMed
TargetThymidine kinase, cytosolic(Rattus norvegicus)
TBA

Curated by ChEMBL
LigandPNGBDBM50205415(({[({[(2R,3S,4R,5R)-3,4-dihydroxy-5-(5-methyl-2,4-...)copy SMILEScopy InChI
Affinity DataKi:  6.50E+3nMAssay Description:Evaluated for the Non-competitive inhibition constant Ki against TdR varied rat cytoplasmic soluble thymidine kinaseMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2BZ66M6PubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus 1)
Max-Delbr�ck-Centrum f�r Molekulare Medizin

Curated by ChEMBL
LigandPNGBDBM50205415(({[({[(2R,3S,4R,5R)-3,4-dihydroxy-5-(5-methyl-2,4-...)copy SMILEScopy InChI
Affinity DataIC50: 2.00E+5nMAssay Description:Compound was evaluated for 50% inhibition of HIV-RT (HIV reverse transcriptase)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FT8MQTPubMed
TargetDNA polymerase alpha catalytic subunit(Homo sapiens (Human))
Max-Delbr�ck-Centrum f�r Molekulare Medizin

Curated by ChEMBL
LigandPNGBDBM50205415(({[({[(2R,3S,4R,5R)-3,4-dihydroxy-5-(5-methyl-2,4-...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+3nMAssay Description:Compound was evaluated for 50% inhibition of DHBV DNA polymerase (duck hepatitis B virus)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FT8MQTPubMed
TargetReverse transcriptase(Human immunodeficiency virus 1)
Veterans Affairs Medical Center

Curated by ChEMBL
LigandPNGBDBM50205415(({[({[(2R,3S,4R,5R)-3,4-dihydroxy-5-(5-methyl-2,4-...)copy SMILEScopy InChI
Affinity DataKd:  2.10E+3nMAssay Description:Binding affinity to HIV1 reverse transcriptase assessed as L-3'-azido-NTP incorporation in nascent DNAMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2RN3BQPPubMed
TargetP2Y purinoceptor 2(Homo sapiens (Human))
National Institute of Diabetes and Digestive and Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50205415(({[({[(2R,3S,4R,5R)-3,4-dihydroxy-5-(5-methyl-2,4-...)copy SMILEScopy InChI
Affinity DataEC50:  480nMAssay Description:Agonist activity at human recombinant P2Y2 receptor expressed in 1321N1 cells assessed as stimulation of phospholipase CMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PK0GZ1PubMed
TargetP2Y purinoceptor 6(Homo sapiens (Human))
National Institute of Diabetes and Digestive and Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50205415(({[({[(2R,3S,4R,5R)-3,4-dihydroxy-5-(5-methyl-2,4-...)copy SMILEScopy InChI
Affinity DataEC50:  140nMAssay Description:Agonist activity at human recombinant P2Y6 receptor expressed in 1321N1 cells assessed as stimulation of phospholipase CMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PK0GZ1PubMed
TargetP2Y purinoceptor 4(Homo sapiens (Human))
National Institute of Diabetes and Digestive and Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50205415(({[({[(2R,3S,4R,5R)-3,4-dihydroxy-5-(5-methyl-2,4-...)copy SMILEScopy InChI
Affinity DataEC50:  3.90E+3nMAssay Description:Agonist activity at human recombinant P2Y4 receptor expressed in 1321N1 cells assessed as stimulation of phospholipase CMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PK0GZ1PubMed
TargetReverse transcriptase protein(Human immunodeficiency virus 1)
Veterans Affairs Medical Center

Curated by ChEMBL
LigandPNGBDBM50205415(({[({[(2R,3S,4R,5R)-3,4-dihydroxy-5-(5-methyl-2,4-...)copy SMILEScopy InChI
Affinity DataKd:  2.90E+3nMAssay Description:Binding affinity to HIV1 reverse transcriptase M184V mutant assessed as L-3'-azido-NTP incorporation in nascent DNAMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2RN3BQPPubMed
TargetDNA polymerase alpha catalytic subunit(Homo sapiens (Human))
Max-Delbr�ck-Centrum f�r Molekulare Medizin

Curated by ChEMBL
LigandPNGBDBM50205415(({[({[(2R,3S,4R,5R)-3,4-dihydroxy-5-(5-methyl-2,4-...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+3nMAssay Description:Compound was evaluated for 50% inhibition of DHBV DNA polymerase (duck hepatitis B virus)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FT8MQTPubMed
TargetDNA polymerase subunit gamma-1(Homo sapiens (Human))
Max-Delbr�ck-Centrum f�r Molekulare Medizin

Curated by ChEMBL
LigandPNGBDBM50205415(({[({[(2R,3S,4R,5R)-3,4-dihydroxy-5-(5-methyl-2,4-...)copy SMILEScopy InChI
Affinity DataIC50: 8.00E+4nMAssay Description:Compound was evaluated for the inhibition of cellular DNA polymerase (gamma)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FT8MQTPubMed
TargetDNA polymerase beta(Homo sapiens (Human))
Max-Delbr�ck-Centrum f�r Molekulare Medizin

Curated by ChEMBL
LigandPNGBDBM50205415(({[({[(2R,3S,4R,5R)-3,4-dihydroxy-5-(5-methyl-2,4-...)copy SMILEScopy InChI
Affinity DataIC50: 2.00E+5nMAssay Description:Compound was evaluated for the inhibition of cellular DNA polymerase (beta)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FT8MQTPubMed