null

SMILES Fc1cccc(Cl)c1Nc1nc2cc(C(=O)Nc3ccc(C#CC4CC4)c(F)c3)c3OCCOc3c2[nH]1

InChI Key InChIKey=CSOLVYOAIFCMHY-UHFFFAOYSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50207322   

TargetProstaglandin E synthase(Homo sapiens (Human))
Glenmark Pharmaceuticals Limited

Curated by ChEMBL
LigandPNGBDBM50207322(CHEMBL3916119)copy SMILEScopy InChI
Affinity DataIC50: 3.60nMAssay Description:Inhibition of human recombinant mPGES-1 expressed in CHO cells assessed as reduction in conversion of PGH2 to PGE2 incubated for 10 mins followed by ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XK8HJ8PubMed
TargetProstaglandin E synthase(Homo sapiens (Human))
Glenmark Pharmaceuticals Limited

Curated by ChEMBL
LigandPNGBDBM50207322(CHEMBL3916119)copy SMILEScopy InChI
Affinity DataIC50: 277nMAssay Description:Inhibition of mPGES-1 in human whole blood assessed as reduction in LPS-induced PGE2 production preincubated followed by LPS stimulation for 20 to 24...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XK8HJ8PubMed
TargetProstaglandin E synthase(Homo sapiens (Human))
Glenmark Pharmaceuticals Limited

Curated by ChEMBL
LigandPNGBDBM50207322(CHEMBL3916119)copy SMILEScopy InChI
Affinity DataIC50: 16nMAssay Description:Inhibition of mPGES-1 in human A549 cells assessed as reduction in interleukin-1 beta-induced PGE2 production incubated for 30 mins followed by IL-1b...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XK8HJ8PubMed