null
SMILES Fc1cccc(Cl)c1Nc1nc2cc(C(=O)Nc3ccc(C#CC4CC4)c(F)c3)c3OCCOc3c2[nH]1
InChI Key InChIKey=CSOLVYOAIFCMHY-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 3 hits for monomerid = 50207322
TargetProstaglandin E synthase(Homo sapiens (Human))
Glenmark Pharmaceuticals Limited
Curated by ChEMBL
Glenmark Pharmaceuticals Limited
Curated by ChEMBL
Affinity DataIC50: 3.60nMAssay Description:Inhibition of human recombinant mPGES-1 expressed in CHO cells assessed as reduction in conversion of PGH2 to PGE2 incubated for 10 mins followed by ...More data for this Ligand-Target Pair
TargetProstaglandin E synthase(Homo sapiens (Human))
Glenmark Pharmaceuticals Limited
Curated by ChEMBL
Glenmark Pharmaceuticals Limited
Curated by ChEMBL
Affinity DataIC50: 277nMAssay Description:Inhibition of mPGES-1 in human whole blood assessed as reduction in LPS-induced PGE2 production preincubated followed by LPS stimulation for 20 to 24...More data for this Ligand-Target Pair
TargetProstaglandin E synthase(Homo sapiens (Human))
Glenmark Pharmaceuticals Limited
Curated by ChEMBL
Glenmark Pharmaceuticals Limited
Curated by ChEMBL
Affinity DataIC50: 16nMAssay Description:Inhibition of mPGES-1 in human A549 cells assessed as reduction in interleukin-1 beta-induced PGE2 production incubated for 30 mins followed by IL-1b...More data for this Ligand-Target Pair