null

SMILES CCOc1cc2ncnc(NC3=CC(=O)C(OCc4cccc(Cl)c4)=CC3=O)c2cc1NC(=O)\C=C\CN(C)C

InChI Key InChIKey=CYNKFMRSHNIJPN-RMKNXTFCSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50209878   

TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50209878((2E)-N-[4-({4-[(3-chlorobenzyl)oxy]-3,6-dioxocyclo...)copy SMILEScopy InChI
Affinity DataIC50: 179nMAssay Description:Inhibition of human VEGFR2 in presence of 1 mM ATPMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GF0VB8PubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50209878((2E)-N-[4-({4-[(3-chlorobenzyl)oxy]-3,6-dioxocyclo...)copy SMILEScopy InChI
Affinity DataIC50: 35.6nMAssay Description:Inhibition of human EGFR in presence of 1 mM ATPMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GF0VB8PubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50209878((2E)-N-[4-({4-[(3-chlorobenzyl)oxy]-3,6-dioxocyclo...)copy SMILEScopy InChI
Affinity DataIC50: 80.2nMAssay Description:Inhibition of human VEGFR2 in presence of 1 uM ATPMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GF0VB8PubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50209878((2E)-N-[4-({4-[(3-chlorobenzyl)oxy]-3,6-dioxocyclo...)copy SMILEScopy InChI
Affinity DataIC50: 12.2nMAssay Description:Inhibition of human EGFR in presence of 1 uM ATPMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GF0VB8PubMed