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SMILES [#7]-[#6]-[#6]-[#6]-[#6]-[#6]-[#6]-[#6]\[#7]=[#6](/[#7])-[#7]

InChI Key InChIKey=YAOAMZOGXBMLFQ-UHFFFAOYSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50216786   

TargetDeoxyhypusine synthase(Plasmodium falciparum)
Institute for Medical Parasitology

Curated by ChEMBL
LigandPNGBDBM50216786(CHEMBL229457 | N-(7-Amino-heptyl)-guanidine | N-gu...)copy SMILEScopy InChI
Affinity DataKi:  100nMAssay Description:Inhibition of recombinant deoxyhypusine synthase in Plasmodium falciparum NF54More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20Z7305PubMed
TargetDeoxyhypusine synthase(Homo sapiens)TBA
LigandPNGBDBM50216786(CHEMBL229457 | N-(7-Amino-heptyl)-guanidine | N-gu...)copy SMILEScopy InChI
Affinity DataIC50: 1.72E+3nMAssay Description:Inhibition of DHPS (unknown origin ) incubated for 30 mins by NAD/NADH-Glow assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2BV7MH5PubMed
TargetDeoxyhypusine synthase(Homo sapiens)TBA
LigandPNGBDBM50216786(CHEMBL229457 | N-(7-Amino-heptyl)-guanidine | N-gu...)copy SMILEScopy InChI
Affinity DataIC50: 500nMAssay Description:Competitive inhibition of human N-terminal His6-tagged TEV protease site linked DHPS expressed in Escherichia coli BL21 (DE3) assessed as reduction i...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2K35Z1VPubMed
TargetDeoxyhypusine synthase(Rattus norvegicus)
National Institute of Dental Research

Curated by ChEMBL
LigandPNGBDBM50216786(CHEMBL229457 | N-(7-Amino-heptyl)-guanidine | N-gu...)copy SMILEScopy InChI
Affinity DataIC50: 30nMAssay Description:In vitro IC50 value by measuring the inhibition of deoxyhypusine synthase.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2P55MJ2PubMedMMDB
TargetDeoxyhypusine synthase(Homo sapiens)TBA
LigandPNGBDBM50216786(CHEMBL229457 | N-(7-Amino-heptyl)-guanidine | N-gu...)copy SMILEScopy InChI
Affinity DataIC50: 140nMAssay Description:Inhibition of human N-terminal His6-tagged TEV protease site linked DHPS expressed in Escherichia coli BL21 (DE3) assessed as reduction in radiolabel...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2K35Z1VPubMed