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SMILES Oc1ccc(cc1)-c1coc2cc(O)c(O)cc2c1=O

InChI Key InChIKey=GYLUFQJZYAJQDI-UHFFFAOYSA-N

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 9 hits for monomerid = 50222303   

TargetPolyunsaturated fatty acid lipoxygenase ALOX15B(Homo sapiens (Human))
Universidad de Santiago

LigandPNGBDBM50222303(4',6,7,-trihydroxyisoflavone | 4',6,7-trihydroxyis...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+5nMpH: 7.3 T: 2°CAssay Description:The reactions were done in a volume of 2 mL and constantly stirred using a magnetic stir bar at room temperature (23 °C). Reactions with the crude, a...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PZ57JFPubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
Universidad de Santiago

LigandPNGBDBM50222303(4',6,7,-trihydroxyisoflavone | 4',6,7-trihydroxyis...)copy SMILEScopy InChI
Affinity DataIC50: 4.00E+4nMpH: 7.3 T: 2°CAssay Description:The reactions were done in a volume of 2 mL and constantly stirred using a magnetic stir bar at room temperature (23 °C). Reactions with the crude, a...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PZ57JFPubMed
TargetPolyunsaturated fatty acid lipoxygenase ALOX15B(Homo sapiens (Human))
Universidad de Santiago

LigandPNGBDBM50222303(4',6,7,-trihydroxyisoflavone | 4',6,7-trihydroxyis...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of 15-hLO2More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2RN37KNPubMed
TargetPolyunsaturated fatty acid lipoxygenase ALOX15(Homo sapiens (Human))
Universidad de Santiago de Chile

Curated by ChEMBL
LigandPNGBDBM50222303(4',6,7,-trihydroxyisoflavone | 4',6,7-trihydroxyis...)copy SMILEScopy InChI
Affinity DataIC50: 4.90E+4nMAssay Description:Inhibition of 15-hLO1More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2RN37KNPubMed
TargetDNA topoisomerase 2-alpha(Homo sapiens (Human))
University of Illinois at Chicago

Curated by ChEMBL
LigandPNGBDBM50222303(4',6,7,-trihydroxyisoflavone | 4',6,7-trihydroxyis...)copy SMILEScopy InChI
Affinity DataIC50: 1.62E+5nMAssay Description:Inhibition of human DNA topoisomerase 2 catalytic domain-mediated knotted bacteriophage P4Virl dell0 DNA unknotting by agarose gel electrophoresisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2SQ936BPubMed
TargetXanthine dehydrogenase/oxidase(Homo sapiens (Human))
AmorePacific Corporation

Curated by ChEMBL
LigandPNGBDBM50222303(4',6,7,-trihydroxyisoflavone | 4',6,7-trihydroxyis...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+6nMAssay Description:Inhibition of xanthine oxidase (unknown origin) assessed as decrease of superoxide generationMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QF8SQKPubMed
TargetXanthine dehydrogenase/oxidase(Homo sapiens (Human))
AmorePacific Corporation

Curated by ChEMBL
LigandPNGBDBM50222303(4',6,7,-trihydroxyisoflavone | 4',6,7-trihydroxyis...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+6nMAssay Description:Inhibition of xanthine oxidase (unknown origin) assessed as decrease of uric acid generationMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QF8SQKPubMed
TargetTyrosinase(Mus musculus (Mouse))
AmorePacific Corporation

Curated by ChEMBL
LigandPNGBDBM50222303(4',6,7,-trihydroxyisoflavone | 4',6,7-trihydroxyis...)copy SMILEScopy InChI
Affinity DataIC50: 5.00E+5nMAssay Description:Inhibition of tyrosinase in mouse Melan-a cells by ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2M045JZPubMed
TargetPolyunsaturated fatty acid lipoxygenase ALOX12(Homo sapiens (Human))
Universidad de Santiago de Chile

Curated by ChEMBL
LigandPNGBDBM50222303(4',6,7,-trihydroxyisoflavone | 4',6,7-trihydroxyis...)copy SMILEScopy InChI
Affinity DataIC50: 8.70E+3nMAssay Description:Inhibition of 12-hLOMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2RN37KNPubMed