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SMILES COc1ccccc1N1CCN(CCCCOc2ccc3ccnn3c2)CC1

InChI Key InChIKey=VIESVSSRMWPJQT-UHFFFAOYSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 15 hits for monomerid = 50236737   

TargetD(4) dopamine receptor(Homo sapiens (Human))
Friedrich-Alexander University Erlangen-N£rnberg

Curated by ChEMBL
LigandPNGBDBM50236737(CHEMBL4098803)copy SMILEScopy InChI
Affinity DataKi:  0.690nMAssay Description:Displacement of [3H]spiperone from human Dopamine D4 receptor expressed in CHO cell membranes after 2 hrs by scintillation counting analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CJ8GR7PubMed
TargetD(2) dopamine receptor(Homo sapiens (Human))
Friedrich-Alexander University Erlangen-N£rnberg

Curated by ChEMBL
LigandPNGBDBM50236737(CHEMBL4098803)copy SMILEScopy InChI
Affinity DataKi:  0.740nMAssay Description:Displacement of [3H]spiperone from human Dopamine D2S receptor expressed in CHO cell membranes after 2 hrs by scintillation counting analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CJ8GR7PubMed
TargetD(2) dopamine receptor(Homo sapiens (Human))
Friedrich-Alexander University Erlangen-N£rnberg

Curated by ChEMBL
LigandPNGBDBM50236737(CHEMBL4098803)copy SMILEScopy InChI
Affinity DataKi:  1.80nMAssay Description:Displacement of [3H]spiperone from human Dopamine D2L receptor expressed in CHO cell membranes after 2 hrs by scintillation counting analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CJ8GR7PubMed
TargetD(3) dopamine receptor(Homo sapiens (Human))
Friedrich-Alexander University Erlangen-N£rnberg

Curated by ChEMBL
LigandPNGBDBM50236737(CHEMBL4098803)copy SMILEScopy InChI
Affinity DataKi:  5nMAssay Description:Displacement of [3H]spiperone from human Dopamine D3 receptor expressed in CHO cell membranes after 2 hrs by scintillation counting analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CJ8GR7PubMed
Target5-hydroxytryptamine receptor 2A(Homo sapiens (Human))
Friedrich-Alexander University Erlangen-N£rnberg

Curated by ChEMBL
LigandPNGBDBM50236737(CHEMBL4098803)copy SMILEScopy InChI
Affinity DataKi:  210nMAssay Description:Displacement of [3H]ketanserin from human 5-HT2A receptor expressed in HEK293T cell membranes after 2 hrs by scintillation counting analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CJ8GR7PubMed
TargetD(1A) dopamine receptor(Homo sapiens (Human))
Friedrich-Alexander University Erlangen-N£rnberg

Curated by ChEMBL
LigandPNGBDBM50236737(CHEMBL4098803)copy SMILEScopy InChI
Affinity DataKi:  1.10E+3nMAssay Description:Displacement of [3H]SCH23390 from human Dopamine D1 receptor expressed in HEK293T cell membranes after 2 hrs by scintillation counting analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CJ8GR7PubMed
TargetD(2) dopamine receptor(Homo sapiens (Human))
Friedrich-Alexander University Erlangen-N£rnberg

Curated by ChEMBL
LigandPNGBDBM50236737(CHEMBL4098803)copy SMILEScopy InChI
Affinity DataEC50:  4.10nMAssay Description:Agonist activity at human Dopamine D2S receptor expressed in HEK293T cell membranes coexpressing GalphaoA incubated for 30 mins measured after 75 min...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CJ8GR7PubMed
TargetD(2) dopamine receptor(Homo sapiens (Human))
Friedrich-Alexander University Erlangen-N£rnberg

Curated by ChEMBL
LigandPNGBDBM50236737(CHEMBL4098803)copy SMILEScopy InChI
Affinity DataEC50:  5nMAssay Description:Agonist activity at N-terminal flag-tagged D2S receptor (unknown origin) expressed in HEK293 cells coexpressing renilla luciferase 2-tagged Galphai3 ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CJ8GR7PubMed
TargetD(2) dopamine receptor(Homo sapiens (Human))
Friedrich-Alexander University Erlangen-N£rnberg

Curated by ChEMBL
LigandPNGBDBM50236737(CHEMBL4098803)copy SMILEScopy InChI
Affinity DataEC50:  2.10nMAssay Description:Agonist activity at N-terminal flag-tagged D2S receptor (unknown origin) expressed in HEK293 cells coexpressing renilla luciferase 2-tagged Galphai1 ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CJ8GR7PubMed
TargetD(2) dopamine receptor(Homo sapiens (Human))
Friedrich-Alexander University Erlangen-N£rnberg

Curated by ChEMBL
LigandPNGBDBM50236737(CHEMBL4098803)copy SMILEScopy InChI
Affinity DataEC50:  23nMAssay Description:Agonist activity at human Dopamine D2S receptor expressed in HEK293T cell membranes coexpressing Galphai2 incubated for 30 mins measured after 75 min...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CJ8GR7PubMed
TargetD(3) dopamine receptor(Homo sapiens (Human))
Friedrich-Alexander University Erlangen-N£rnberg

Curated by ChEMBL
LigandPNGBDBM50236737(CHEMBL4098803)copy SMILEScopy InChI
Affinity DataEC50:  29nMAssay Description:Functional cocaine antagonism was evaluated by inhibition of [3H]dopamine reuptakeMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CJ8GR7PubMed
TargetD(3) dopamine receptor(Homo sapiens (Human))
Friedrich-Alexander University Erlangen-N£rnberg

Curated by ChEMBL
LigandPNGBDBM50236737(CHEMBL4098803)copy SMILEScopy InChI
Affinity DataEC50:  29nMAssay Description:Agonist activity at human Dopamine D3 receptor expressed in HEK293T cell membranes coexpressing GalphaoA incubated for 30 mins measured after 75 mins...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CJ8GR7PubMed
TargetD(2) dopamine receptor(Homo sapiens (Human))
Friedrich-Alexander University Erlangen-N£rnberg

Curated by ChEMBL
LigandPNGBDBM50236737(CHEMBL4098803)copy SMILEScopy InChI
Affinity DataEC50:  4.40nMAssay Description:Concentration required for the inhibitory activity against human FarnesyltransferaseMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CJ8GR7PubMed
TargetD(2) dopamine receptor(Homo sapiens (Human))
Friedrich-Alexander University Erlangen-N£rnberg

Curated by ChEMBL
LigandPNGBDBM50236737(CHEMBL4098803)copy SMILEScopy InChI
Affinity DataEC50:  1.90nMAssay Description:In vitro binding affinity against Tachykinin receptor 1 in rabbit whole brain membranes using [3H][Sar9Met(O2)]-SP binding assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CJ8GR7PubMed
TargetD(2) dopamine receptor(Homo sapiens (Human))
Friedrich-Alexander University Erlangen-N£rnberg

Curated by ChEMBL
LigandPNGBDBM50236737(CHEMBL4098803)copy SMILEScopy InChI
Affinity DataEC50:  1.90nMAssay Description:In vitro binding affinity against Tachykinin receptor 1 in rabbit whole brain membranes using [3H][Sar9Met(O2)]-SP binding assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CJ8GR7PubMed