null
SMILES N[C@H]1C[C@@H]1c1ccccc1
InChI Key InChIKey=AELCINSCMGFISI-BDAKNGLRSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 42 hits for monomerid = 50236898
TargetAmine oxidase [flavin-containing] B(Homo sapiens (Human))
Kyoto Prefectural University of Medicine
Curated by ChEMBL
Kyoto Prefectural University of Medicine
Curated by ChEMBL
Affinity DataKi: 1.60E+4nMAssay Description:Inhibition of MAO BMore data for this Ligand-Target Pair
TargetLysine-specific histone demethylase 1A(Homo sapiens (Human))
University of Southampton
Curated by ChEMBL
University of Southampton
Curated by ChEMBL
Affinity DataKi: 2.66E+4nMAssay Description:Inhibition of human recombinant His-tagged full length LSD1 expressed in Escherichia coli BL21 (DE3) assessed as inactivation constant preincubated f...More data for this Ligand-Target Pair
TargetLysine-specific histone demethylase 1A(Homo sapiens (Human))
University of Southampton
Curated by ChEMBL
University of Southampton
Curated by ChEMBL
Affinity DataKi: 2.81E+4nMAssay Description:Inhibition of human recombinant His-tagged full length LSD1 expressed in Escherichia coli BL21 (DE3) assessed as inactivation constant preincubated f...More data for this Ligand-Target Pair
TargetAmine oxidase [flavin-containing] A(Homo sapiens (Human))
Kyoto Prefectural University of Medicine
Curated by ChEMBL
Kyoto Prefectural University of Medicine
Curated by ChEMBL
Affinity DataKi: 1.02E+5nMAssay Description:Inhibition of MAO AMore data for this Ligand-Target Pair
TargetLysine-specific histone demethylase 1A(Homo sapiens (Human))
University of Southampton
Curated by ChEMBL
University of Southampton
Curated by ChEMBL
Affinity DataKi: 1.68E+5nMAssay Description:Inhibition of human truncated LSD1 lacking N-terminal 184 amino acidsMore data for this Ligand-Target Pair
TargetLysine-specific histone demethylase 1A(Homo sapiens (Human))
University of Southampton
Curated by ChEMBL
University of Southampton
Curated by ChEMBL
Affinity DataKi: 1.68E+5nMAssay Description:Inhibition of human truncated LSD1 lacking N-terminal 184 amino acidsMore data for this Ligand-Target Pair
TargetLysine-specific histone demethylase 1A(Homo sapiens (Human))
University of Southampton
Curated by ChEMBL
University of Southampton
Curated by ChEMBL
TargetLysine-specific histone demethylase 1A(Homo sapiens (Human))
University of Southampton
Curated by ChEMBL
University of Southampton
Curated by ChEMBL
Affinity DataIC50: 1.57E+4nMAssay Description:Inhibition of LSD1 (unknown origin)More data for this Ligand-Target Pair
TargetAmine oxidase [flavin-containing] A(Rattus norvegicus (rat))
Baylor College of Medicine
Curated by ChEMBL
Baylor College of Medicine
Curated by ChEMBL
Affinity DataIC50: 290nMAssay Description:Inhibition of rat MAO-A using serotonin as substrate incubated for 1 hrMore data for this Ligand-Target Pair
TargetLysine-specific histone demethylase 1A(Homo sapiens (Human))
University of Southampton
Curated by ChEMBL
University of Southampton
Curated by ChEMBL
Affinity DataIC50: 4.10E+4nMAssay Description:Inhibition of full length N-terminal His-tagged human recombinant LSD1 (1 to 852 residues) expressed in Escherichia coli BL21(DE3) cells using H3K4me...More data for this Ligand-Target Pair
TargetAmine oxidase [flavin-containing] B(Homo sapiens (Human))
Kyoto Prefectural University of Medicine
Curated by ChEMBL
Kyoto Prefectural University of Medicine
Curated by ChEMBL
Affinity DataIC50: 3.50E+3nMAssay Description:Inhibition of human recombinant MAO-B expressed in baculovirus infected BTI insect cells using (4S)-4,5-dihydro-2-(6-hydroxybenzothiazolyl)-4-thiazol...More data for this Ligand-Target Pair
TargetAmine oxidase [flavin-containing] A(Homo sapiens (Human))
Kyoto Prefectural University of Medicine
Curated by ChEMBL
Kyoto Prefectural University of Medicine
Curated by ChEMBL
Affinity DataIC50: 4.20E+3nMAssay Description:Inhibition of human recombinant MAO-A expressed in baculovirus infected BTI insect cells using (4S)-4,5-dihydro-2-(6-hydroxybenzothiazolyl)-4-thiazol...More data for this Ligand-Target Pair
TargetLysine-specific histone demethylase 1A(Homo sapiens (Human))
University of Southampton
Curated by ChEMBL
University of Southampton
Curated by ChEMBL
Affinity DataIC50: 2.10E+4nMAssay Description:Inhibition of partially purified LSD1 using histone H3K4Me2 peptide substrate by peroxidase-coupled assayMore data for this Ligand-Target Pair
TargetAmine oxidase [flavin-containing] B(Homo sapiens (Human))
Kyoto Prefectural University of Medicine
Curated by ChEMBL
Kyoto Prefectural University of Medicine
Curated by ChEMBL
Affinity DataIC50: 8.51nMT: 2°CAssay Description:The MAO-A and MAO-B screening biochemical assay was completed by Reaction Biology Corp. with the same assay format with LSD1 assay, and the detailed ...More data for this Ligand-Target Pair
TargetAmine oxidase [flavin-containing] A(Homo sapiens (Human))
Kyoto Prefectural University of Medicine
Curated by ChEMBL
Kyoto Prefectural University of Medicine
Curated by ChEMBL
Affinity DataIC50: 64.6nMT: 2°CAssay Description:The MAO-A and MAO-B screening biochemical assay was completed by Reaction Biology Corp. with the same assay format with LSD1 assay, and the detailed ...More data for this Ligand-Target Pair
TargetLysine-specific histone demethylase 1A(Homo sapiens (Human))
University of Southampton
Curated by ChEMBL
University of Southampton
Curated by ChEMBL
TargetLysine-specific histone demethylase 1A(Homo sapiens (Human))
University of Southampton
Curated by ChEMBL
University of Southampton
Curated by ChEMBL
Affinity DataIC50: 4.64E+3nMpH: 7.5 T: 2°CAssay Description:Briefly, the compounds in DMSO were added into the LSD1 in the reaction buffer consisting of 50 mM Tris¿HCl, pH 7.5, and 1% DMSO, using Acoustic Tech...More data for this Ligand-Target Pair
Affinity DataIC50: 6.96E+3nMAssay Description:Inhibition of human CYP2B6More data for this Ligand-Target Pair
Affinity DataIC50: 3.04E+3nMAssay Description:Inhibition of human CYP2C19More data for this Ligand-Target Pair
Affinity DataIC50: 1.03E+5nMAssay Description:Inhibition of human BSEP expressed in baculovirus transfected fall armyworm Sf21 cell membranes vesicles assessed as reduction in ATP-dependent [3H]-...More data for this Ligand-Target Pair
TargetAmine oxidase [flavin-containing] A(Homo sapiens (Human))
Kyoto Prefectural University of Medicine
Curated by ChEMBL
Kyoto Prefectural University of Medicine
Curated by ChEMBL
Affinity DataIC50: 3.40E+3nMAssay Description:Inhibition of MAO-A (unknown origin) using beetle luciferin derived luminogenic substrate preincubated for 15 mins followed by substrate addition mea...More data for this Ligand-Target Pair
TargetLysine-specific histone demethylase 1A(Homo sapiens (Human))
University of Southampton
Curated by ChEMBL
University of Southampton
Curated by ChEMBL
Affinity DataIC50: 6.30E+3nMAssay Description:Inhibition of LSD1 (unknown origin)More data for this Ligand-Target Pair
TargetLysine-specific histone demethylase 1A(Homo sapiens (Human))
University of Southampton
Curated by ChEMBL
University of Southampton
Curated by ChEMBL
Affinity DataIC50: 6.50E+3nMAssay Description:Inhibition of GST-tagged LSD1 (2 to 852 residues) (unknown origin) expressed in baculovirus infected sf9 cells preincubated for 15 mins followed by H...More data for this Ligand-Target Pair
TargetLysine-specific histone demethylase 1A(Homo sapiens (Human))
University of Southampton
Curated by ChEMBL
University of Southampton
Curated by ChEMBL
Affinity DataIC50: 3.60E+3nMAssay Description:Inhibition of N-terminal truncated recombinant human LSD1 (151 to 852 residues) expressed in Escherichia coli using histone H3 (1 to 21 residues) K4m...More data for this Ligand-Target Pair
TargetLysine-specific histone demethylase 1A(Homo sapiens (Human))
University of Southampton
Curated by ChEMBL
University of Southampton
Curated by ChEMBL
Affinity DataIC50: 2.78E+4nMAssay Description:Dissociation constant against galectin-3 using competitive fluorescence polarizationMore data for this Ligand-Target Pair
Affinity DataKd: 1.32E+7nMAssay Description:Binding affinity against trypsinMore data for this Ligand-Target Pair
Affinity DataIC50: 2.07E+4nMAssay Description:Inhibition of recombinant LSD1/CoREST (unknown origin) assessed as residual activity for 30 mins to 4 hrs by fluorescence based assay relative to con...More data for this Ligand-Target Pair
TargetAmine oxidase [flavin-containing] B(Homo sapiens (Human))
Kyoto Prefectural University of Medicine
Curated by ChEMBL
Kyoto Prefectural University of Medicine
Curated by ChEMBL
Affinity DataIC50: 5.80E+3nMAssay Description:Inhibition of MAOB (unknown origin) by luminiscent assayMore data for this Ligand-Target Pair
TargetAmine oxidase [flavin-containing] A(Homo sapiens (Human))
Kyoto Prefectural University of Medicine
Curated by ChEMBL
Kyoto Prefectural University of Medicine
Curated by ChEMBL
Affinity DataIC50: 4.20E+3nMAssay Description:Inhibition of MAOA (unknown origin) by luminiscent assayMore data for this Ligand-Target Pair
TargetLysine-specific histone demethylase 1A(Homo sapiens (Human))
University of Southampton
Curated by ChEMBL
University of Southampton
Curated by ChEMBL
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibition of LSD1More data for this Ligand-Target Pair
TargetLysine-specific histone demethylase 1A(Homo sapiens (Human))
University of Southampton
Curated by ChEMBL
University of Southampton
Curated by ChEMBL
Affinity DataIC50: 4.03E+4nMAssay Description:Inhibition of human recombinant LSD1 using fluorogenic ADHP based substrate preincubated for 30 mins followed by substrate addition measured after 10...More data for this Ligand-Target Pair
TargetLysine-specific histone demethylase 1A(Homo sapiens (Human))
University of Southampton
Curated by ChEMBL
University of Southampton
Curated by ChEMBL
TargetAmine oxidase [flavin-containing] A(Homo sapiens (Human))
Kyoto Prefectural University of Medicine
Curated by ChEMBL
Kyoto Prefectural University of Medicine
Curated by ChEMBL
TargetAmine oxidase [flavin-containing] B(Homo sapiens (Human))
Kyoto Prefectural University of Medicine
Curated by ChEMBL
Kyoto Prefectural University of Medicine
Curated by ChEMBL
TargetAmine oxidase [flavin-containing] A(Homo sapiens (Human))
Kyoto Prefectural University of Medicine
Curated by ChEMBL
Kyoto Prefectural University of Medicine
Curated by ChEMBL
TargetAmine oxidase [flavin-containing] B(Homo sapiens (Human))
Kyoto Prefectural University of Medicine
Curated by ChEMBL
Kyoto Prefectural University of Medicine
Curated by ChEMBL
TargetAmine oxidase [flavin-containing] B(Rattus norvegicus (rat))
Baylor College of Medicine
Curated by ChEMBL
Baylor College of Medicine
Curated by ChEMBL
Affinity DataIC50: 78nMAssay Description:Inhibition of rat MAO-B using benzylamine as substrateMore data for this Ligand-Target Pair
Affinity DataEC50: 1.51E+3nMAssay Description:Agonist activity at human trace amine associated receptor 1 expressed in RD-HGA16 CHO-K1 cells coexpressed with Galpha16 protein assessed as internal...More data for this Ligand-Target Pair
TargetAmine oxidase [flavin-containing] A(Homo sapiens (Human))
Kyoto Prefectural University of Medicine
Curated by ChEMBL
Kyoto Prefectural University of Medicine
Curated by ChEMBL
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of human recombinant MAOAMore data for this Ligand-Target Pair
TargetAmine oxidase [flavin-containing] B(Homo sapiens (Human))
Kyoto Prefectural University of Medicine
Curated by ChEMBL
Kyoto Prefectural University of Medicine
Curated by ChEMBL
Affinity DataIC50: 1.90E+4nMAssay Description:Inhibition of human recombinant MAOBMore data for this Ligand-Target Pair