null
SMILES CCCS(=O)(=O)C[C@H]1C[C@H](C1)N(C)c1ncnc2[nH]ccc12
InChI Key InChIKey=JXXOAWDMPAWACX-TXEJJXNPSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 5 hits for monomerid = 50243858
Affinity DataIC50: 2.00E+5nMAssay Description:Inhibitory activity of the Compound was tested against HIV protease enzyme.(value reported by Roche group)More data for this Ligand-Target Pair
Affinity DataIC50: 550nMAssay Description:Inhibition of recombinant human JAK2 using FITC-KGGEEEEYFELVKK as substrate in presence of 1 mM ATP by mobility shift assayMore data for this Ligand-Target Pair
Affinity DataIC50: 40nMAssay Description:Inhibition of recombinant human JAK1 using 5'FAM-KKSRGDYMTMQID as substrate in presence of 1 mM ATP by mobility shift assayMore data for this Ligand-Target Pair
TargetNon-receptor tyrosine-protein kinase TYK2/Tyrosine-protein kinase JAK1(Homo sapiens (Human))
Pfizer Inc.
Curated by ChEMBL
Pfizer Inc.
Curated by ChEMBL
Affinity DataIC50: 1.40E+3nMAssay Description:Inhibition of JAK1/TYK2 in human whole blood assessed as reduction in IFNalpha induced STAT3 phosphorylation preincubated for 45 mins followed by IFN...More data for this Ligand-Target Pair
Affinity DataIC50: 2.00E+4nMAssay Description:The ability to inhibit [3H]prazosin binding to Alpha-1 adrenergic receptor in rat whole brainMore data for this Ligand-Target Pair