null

SMILES Cc1ccc(C)c(Nc2nccc(n2)-c2nccs2)c1

InChI Key InChIKey=WPPTYGSKZRVJSC-UHFFFAOYSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50249258   

TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Vertex Pharmaceuticals, Inc.

Curated by ChEMBL
LigandPNGBDBM50249258(CHEMBL475570 | N-(2,5-dimethylphenyl)-4-(thiazol-2...)copy SMILEScopy InChI
Affinity DataKi:  153nMAssay Description:Inhibition of SRC (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25Q4VZTPubMed
TargetTyrosine-protein kinase SYK(Homo sapiens (Human))
Vertex Pharmaceuticals, Inc.

Curated by ChEMBL
LigandPNGBDBM50249258(CHEMBL475570 | N-(2,5-dimethylphenyl)-4-(thiazol-2...)copy SMILEScopy InChI
Affinity DataKi:  1.82E+3nMAssay Description:Inhibition of SYK (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25Q4VZTPubMed
TargetCyclin-dependent kinase 2(Homo sapiens (Human))
Vertex Pharmaceuticals, Inc.

Curated by ChEMBL
LigandPNGBDBM50249258(CHEMBL475570 | N-(2,5-dimethylphenyl)-4-(thiazol-2...)copy SMILEScopy InChI
Affinity DataKi: >5.00E+3nMAssay Description:Inhibition of CDK2 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25Q4VZTPubMed
TargetTyrosine-protein kinase SYK(Homo sapiens (Human))
Vertex Pharmaceuticals, Inc.

Curated by ChEMBL
LigandPNGBDBM50249258(CHEMBL475570 | N-(2,5-dimethylphenyl)-4-(thiazol-2...)copy SMILEScopy InChI
Affinity DataIC50: 1.82E+3nMAssay Description:Inhibition of recombinant Syk (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2WM1D98PubMed