null
SMILES CN1C(=O)NC(=O)[C@]11Cc2ccc(NC(=O)Cn3c4cc(C)cc5NC(=O)Cn(c45)c3=O)cc2C1
InChI Key InChIKey=UIJJWQFJVGLSOH-XMMPIXPASA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 6 hits for monomerid = 50254446
TargetCalcitonin gene-related peptide type 1 receptor(Homo sapiens (Human))
Merck& Co
Curated by ChEMBL
Merck& Co
Curated by ChEMBL
Affinity DataKi: 0.510nMAssay Description:Displacement of [125I]hCGRP from human CGRP receptor expressed in HEK293 cells coexpressing RAMP1More data for this Ligand-Target Pair
TargetCalcitonin gene-related peptide type 1 receptor(Homo sapiens (Human))
Merck& Co
Curated by ChEMBL
Merck& Co
Curated by ChEMBL
Affinity DataKi: 0.510nMAssay Description:Displacement of [125I]hCGRP from human CGRP receptor expressed in HEK293 cells coexpressing RAMP1More data for this Ligand-Target Pair
TargetCalcitonin gene-related peptide type 1 receptor(Homo sapiens (Human))
Merck& Co
Curated by ChEMBL
Merck& Co
Curated by ChEMBL
Affinity DataIC50: 5.40nMAssay Description:Antagonistic activity at human CGRP receptor expressed in HEK293 cells coexpressing RAMP1 assessed as inhibition of CGRP-induced cAMP production in p...More data for this Ligand-Target Pair
TargetCalcitonin gene-related peptide type 1 receptor(Homo sapiens (Human))
Merck& Co
Curated by ChEMBL
Merck& Co
Curated by ChEMBL
Affinity DataIC50: 2.40nMAssay Description:Antagonistic activity at human CGRP receptor expressed in HEK293 cells coexpressing RAMP1 assessed as inhibition of CGRP-induced cAMP productionMore data for this Ligand-Target Pair
TargetCalcitonin gene-related peptide type 1 receptor(Homo sapiens (Human))
Merck& Co
Curated by ChEMBL
Merck& Co
Curated by ChEMBL
Affinity DataIC50: 5.40nMAssay Description:Antagonistic activity at human CGRP receptor expressed in HEK293 cells coexpressing RAMP1 assessed as inhibition of CGRP-induced cAMP production in p...More data for this Ligand-Target Pair
TargetCalcitonin gene-related peptide type 1 receptor(Homo sapiens (Human))
Merck& Co
Curated by ChEMBL
Merck& Co
Curated by ChEMBL
Affinity DataIC50: 2.40nMAssay Description:Antagonistic activity at human CGRP receptor expressed in HEK293 cells coexpressing RAMP1 assessed as inhibition of CGRP-induced cAMP productionMore data for this Ligand-Target Pair