null

SMILES CC1(CCCCCCC1)N1CCC(CC1)n1c(nc2ccccc12)[C@H]1CCCNC1

InChI Key InChIKey=CYYNMPPFEJPBJD-NRFANRHFSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 11 hits for monomerid = 50255899   

TargetNociceptin receptor(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50255899(1-[1-(1-Methylcyclooctyl)-4-piperidinyl]-2-[(3S)-3...)copy SMILEScopy InChI
Affinity DataKi:  0.100nMAssay Description:Displacement of [3H]N/OFQ from human NOP receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29K4C5KPubMed
TargetMu-type opioid receptor(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50255899(1-[1-(1-Methylcyclooctyl)-4-piperidinyl]-2-[(3S)-3...)copy SMILEScopy InChI
Affinity DataKi:  0.590nMAssay Description:Agonist activity at human mu opioid receptor expressed in CHOK1 cells by [35S]GTPgammaS bindingMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29K4C5KPubMed
TargetKappa-type opioid receptor(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50255899(1-[1-(1-Methylcyclooctyl)-4-piperidinyl]-2-[(3S)-3...)copy SMILEScopy InChI
Affinity DataKi:  9.20nMAssay Description:Displacement of [3H]enadoline from human kappa opioid receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29K4C5KPubMed
TargetDelta-type opioid receptor(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50255899(1-[1-(1-Methylcyclooctyl)-4-piperidinyl]-2-[(3S)-3...)copy SMILEScopy InChI
Affinity DataKi:  168nMAssay Description:Displacement of [3H]DPDPE from human delta opioid receptor expressed in CHOK1 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29K4C5KPubMed
TargetNociceptin receptor(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50255899(1-[1-(1-Methylcyclooctyl)-4-piperidinyl]-2-[(3S)-3...)copy SMILEScopy InChI
Affinity DataEC50:  1.59E+3nMAssay Description:Agonist activity at human NOPR expressed in human BHK cells assessed as increase in beta-arrestin-2 recruitmentMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2F76GX7PubMed
TargetNociceptin receptor(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50255899(1-[1-(1-Methylcyclooctyl)-4-piperidinyl]-2-[(3S)-3...)copy SMILEScopy InChI
Affinity DataEC50:  0.0251nMAssay Description:Agonist activity at human NOPR expressed in human BHK cells assessed as inhibition of forskolin-mediated cAMP accumulation after 10 mins by radioimmu...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2F76GX7PubMed
TargetNociceptin receptor(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50255899(1-[1-(1-Methylcyclooctyl)-4-piperidinyl]-2-[(3S)-3...)copy SMILEScopy InChI
Affinity DataEC50:  2.46E+3nMAssay Description:Agonist activity at human NOPR expressed in human BHK cells assessed as increase in beta-arrestin-1 recruitmentMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2F76GX7PubMed
TargetNociceptin receptor(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50255899(1-[1-(1-Methylcyclooctyl)-4-piperidinyl]-2-[(3S)-3...)copy SMILEScopy InChI
Affinity DataEC50:  0.5nMAssay Description:Agonist activity at human NOP receptor expressed in HEK293 cells by [35S]GTPgammaS bindingMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29K4C5KPubMed
TargetMu-type opioid receptor(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50255899(1-[1-(1-Methylcyclooctyl)-4-piperidinyl]-2-[(3S)-3...)copy SMILEScopy InChI
Affinity DataEC50:  23nMAssay Description:Agonist activity at human mu opioid receptor expressed in CHOK1 cells by [35S]GTPgammaS bindingMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29K4C5KPubMed
TargetDelta-type opioid receptor(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50255899(1-[1-(1-Methylcyclooctyl)-4-piperidinyl]-2-[(3S)-3...)copy SMILEScopy InChI
Affinity DataEC50:  514nMAssay Description:Agonist activity at human delta opioid receptor expressed in CHOK1 cells by [35S]GTPgammaS bindingMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29K4C5KPubMed
TargetKappa-type opioid receptor(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50255899(1-[1-(1-Methylcyclooctyl)-4-piperidinyl]-2-[(3S)-3...)copy SMILEScopy InChI
Affinity DataEC50:  8.40nMAssay Description:Agonist activity at human kappa opioid receptor expressed in HEK293 cells by [35S]GTPgammaS bindingMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29K4C5KPubMed