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SMILES COc1ccc(cc1)-c1cnc2c(cnn2c1)-c1cccc2ncccc12

InChI Key InChIKey=FVRYPYDPKSZGNS-UHFFFAOYSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50261979   

TargetBone morphogenetic protein 4(Homo sapiens (Human))
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50261979(5-(6-(4-methoxyphenyl)pyrazolo[1,5-a]pyrimidin-3-y...)copy SMILEScopy InChI
Affinity DataIC50: 3.00E+3nMAssay Description:Inhibition of BMP4 (unknown origin)-induced phosphorylation of SMAD 1/5/8 by cytoblot cellular ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2BR8S0VPubMed
TargetSerine/threonine-protein kinase receptor R3(Homo sapiens (Human))
Vanderbilt University Medical Center

Curated by ChEMBL
LigandPNGBDBM50261979(5-(6-(4-methoxyphenyl)pyrazolo[1,5-a]pyrimidin-3-y...)copy SMILEScopy InChI
Affinity DataIC50: 46nMAssay Description:Inhibition of ALK1 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2WW7K3PPubMed
TargetActivin receptor type-1(Homo sapiens (Human))
Vanderbilt University Medical Center

Curated by ChEMBL
LigandPNGBDBM50261979(5-(6-(4-methoxyphenyl)pyrazolo[1,5-a]pyrimidin-3-y...)copy SMILEScopy InChI
Affinity DataIC50: 32nMAssay Description:Inhibition of ALK2 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2WW7K3PPubMed
TargetActivin receptor type-1(Homo sapiens (Human))
Vanderbilt University Medical Center

Curated by ChEMBL
LigandPNGBDBM50261979(5-(6-(4-methoxyphenyl)pyrazolo[1,5-a]pyrimidin-3-y...)copy SMILEScopy InChI
Affinity DataIC50: 32nMMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20C50VHPubMed
TargetBone morphogenetic protein receptor type-1B(Homo sapiens (Human))
Vanderbilt University Medical Center

Curated by ChEMBL
LigandPNGBDBM50261979(5-(6-(4-methoxyphenyl)pyrazolo[1,5-a]pyrimidin-3-y...)copy SMILEScopy InChI
Affinity DataIC50: 9.83E+3nMAssay Description:Inhibition of ALK6 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2WW7K3PPubMed
TargetBone morphogenetic protein 4(Mus musculus)
Vanderbilt University Medical Center

Curated by ChEMBL
LigandPNGBDBM50261979(5-(6-(4-methoxyphenyl)pyrazolo[1,5-a]pyrimidin-3-y...)copy SMILEScopy InChI
Affinity DataIC50: 152nMAssay Description:Inhibition of BMP4 in mouse C2C12BRA cells after 14 hrs by luciferase reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2WW7K3PPubMed
TargetBone morphogenetic protein receptor type-1A(Homo sapiens (Human))
Vanderbilt University Medical Center

Curated by ChEMBL
LigandPNGBDBM50261979(5-(6-(4-methoxyphenyl)pyrazolo[1,5-a]pyrimidin-3-y...)copy SMILEScopy InChI
Affinity DataIC50: 1.08E+4nMAssay Description:Inhibition of ALK3 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2WW7K3PPubMed