null

SMILES C[C@H]1Cc2c(CN1)ncnc2Oc1ccc2n(ccc2c1)C(=O)Nc1cc([nH]n1)C1(C)CC1

InChI Key InChIKey=WFJQCQNBWDAYSK-AWEZNQCLSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50270424   

TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Novartis Institutes for BioMedical Research

Curated by ChEMBL
LigandPNGBDBM50270424(CHEMBL3746776)copy SMILEScopy InChI
Affinity DataIC50: 0.900nMAssay Description:Inhibition of KDR (unknown origin) expressed in mouse Ba/F3 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q22F7QZMPubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Novartis Institutes for BioMedical Research

Curated by ChEMBL
LigandPNGBDBM50270424(CHEMBL3746776)copy SMILEScopy InChI
Affinity DataIC50: 2.74E+4nMAssay Description:Inhibition of human ERG channel by automated Q-patch assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26M39T9PubMed
TargetProto-oncogene tyrosine-protein kinase receptor Ret(Homo sapiens (Human))
Novartis Institutes for BioMedical Research

Curated by ChEMBL
LigandPNGBDBM50270424(CHEMBL3746776)copy SMILEScopy InChI
Affinity DataIC50: 66nMAssay Description:Inhibition of Ret (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26M39T9PubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Novartis Institutes for BioMedical Research

Curated by ChEMBL
LigandPNGBDBM50270424(CHEMBL3746776)copy SMILEScopy InChI
Affinity DataIC50: 8nMAssay Description:Inhibition of KDR (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26M39T9PubMed
TargetPlatelet-derived growth factor receptor alpha(Homo sapiens (Human))
Novartis Institutes for BioMedical Research

Curated by ChEMBL
LigandPNGBDBM50270424(CHEMBL3746776)copy SMILEScopy InChI
Affinity DataIC50: 150nMAssay Description:Inhibition of PDGFRalpha (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26M39T9PubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Novartis Institutes for BioMedical Research

Curated by ChEMBL
LigandPNGBDBM50270424(CHEMBL3746776)copy SMILEScopy InChI
Affinity DataIC50: 0.900nMAssay Description:Inhibition of Tel-fused KDR (unknown origin) expressed in mouse BaF3 cells using poly(Glu,Tyr) as substrate after 10 mins by scintillation counting a...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26M39T9PubMed
TargetMast/stem cell growth factor receptor Kit(Homo sapiens (Human))
Novartis Institutes for BioMedical Research

Curated by ChEMBL
LigandPNGBDBM50270424(CHEMBL3746776)copy SMILEScopy InChI
Affinity DataIC50: 600nMAssay Description:Inhibition of c-Kit (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26M39T9PubMed