null
SMILES N[C@](CC1c2ccccc2Oc2ccccc12)([C@H]1C[C@@H]1C(O)=O)C(O)=O
InChI Key InChIKey=VLZBRVJVCCNPRJ-ZQGRQUNCSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 6 hits for monomerid = 50279772
TargetMetabotropic glutamate receptor 2(Homo sapiens (Human))
Taisho Pharmaceutical Co., Ltd.
Curated by ChEMBL
Taisho Pharmaceutical Co., Ltd.
Curated by ChEMBL
Affinity DataKi: 3.72nMAssay Description:Tested for binding affinity against Metabotropic glutamate receptor 2 in CHO cells using [3H]-7 as radioligandMore data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 3(Rattus norvegicus (Rat))
Taisho Pharmaceutical Co., Ltd.
Curated by ChEMBL
Taisho Pharmaceutical Co., Ltd.
Curated by ChEMBL
Affinity DataKi: 4.11nMAssay Description:Tested for binding affinity against Metabotropic glutamate receptor 3 in CHO cells using [3H]-7 as radioligandMore data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 2(Homo sapiens (Human))
Taisho Pharmaceutical Co., Ltd.
Curated by ChEMBL
Taisho Pharmaceutical Co., Ltd.
Curated by ChEMBL
Affinity DataIC50: 200nMAssay Description:Ability to block 1S,3R-ACPD-induced inhibition of forskolin stimulated cyclic-AMP in non-neuronal cell line expressing human Metabotropic glutamate r...More data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 3(Rattus norvegicus (Rat))
Taisho Pharmaceutical Co., Ltd.
Curated by ChEMBL
Taisho Pharmaceutical Co., Ltd.
Curated by ChEMBL
Affinity DataEC50: 100nMAssay Description:Agonist potency against cloned Metabotropic glutamate receptor 3More data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 2(Homo sapiens (Human))
Taisho Pharmaceutical Co., Ltd.
Curated by ChEMBL
Taisho Pharmaceutical Co., Ltd.
Curated by ChEMBL
Affinity DataEC50: 50.3nMAssay Description:Antagonist activity against Metabotropic glutamate receptor 2
expressed in CHO cells was evaluated in presence of 30 microM glutamic acidMore data for this Ligand-Target Pair
expressed in CHO cells was evaluated in presence of 30 microM glutamic acidMore data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 3(Homo sapiens (Human))
Lilly Research Laboratories
Curated by ChEMBL
Lilly Research Laboratories
Curated by ChEMBL
Affinity DataIC50: 16nMAssay Description:Ability to block 1S,3R-ACPD-induced inhibition of forskolin stimulated cyclic-AMP in non-neuronal cell line expressing human Metabotropic glutamate r...More data for this Ligand-Target Pair